Senior Associate Scientist - Flow Cytometry

About the role

The Immunotox group supports drug development by investigating immune responses using flow cytometry. The group supports immunophenotyping endpoints, isolation of PBMCs and cell-based stimulation assays. Utilizing these platforms/assays, the team is responsible for the method development, validation and routine sample analysis in both the regulated and non-regulated space of non-clinical studies.

Responsibilities

• Effectively manage a portfolio of sample analysis projects while ensuring timelines are met in a single operational area with oversight
• Execute review and approval of data with oversight for final scientific/technical decisions within a single operational area
• Develop understanding of compliance expectations to respond to quality assurance audit observations in appropriate software with oversight
• Afford assistance with oversight the completion of laboratory investigations, assay troubleshooting and quality observations
• Afford assistance in problem solving for technical and/or regulatory issues with oversight
• Assist in writing and preparing study plans/protocols/amendments with minimal oversight
• Afford participation in Sponsor visits/tours with minimal oversight
• Afford development of expertise in developing and validating quantitative/qualitative methods/procedures with limited complexity/scope in one operational area with minimal oversight
• Afford performance of data analysis using appropriate software with minimal oversight
• Afford development of critical thinking, troubleshooting and time management skills aligned with needs of operational areas
• Afford demonstration of effective communication skills through informal discussions with peers, supervisor, and team; Function as a liaison, maintaining timely and frequent communication between CRL andSponsor/Client/SD with minimal oversight
• Afford ensure scientific integrity of studies with minimal oversight
• Afford function as a Principal Investigator, Individual Scientist and/or Study Director as assigned with minimal oversight
• Afford active communication and collaboration across operational areas in order to adhere to timelines and produce quality data
• Afford efficient performance and documentation of all procedures, materials and results in compliance with applicable regulatory standards as applicable (protocols, methods, SOPs, etc.)
• Afford write, review and approve deviations with oversight
• Afford develop knowledge of regulatory and GXP requirements, industry standards and company SOPs within one operational area
• Afford effectively manage a small portfolio of research projects including method development and validation while ensuring timelines are met in a single operational area with oversight

Requirements

• Bachelor’s degree (BA/BS) with 5-7 years of relevant working experience. Master’s degree (MS) with 1-2 years of relevant work experience. Doctorate degree (PhD) with no experience
• Ability to communicate verbally and in writing at all levels inside and outside the organization
• Basic familiarity with Microsoft Office Suite
• Computer skills, commensurate with Essential Functions, including the ability to learn a validated system
• Able to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts Sometimes on short notice
• Able to work under specific time constraints
• Must be authorized to work in the United States without a sponsor visa, now or in the future

Qualifications

• Bachelor’s degree (BA/BS) with 5-7 years of relevant working experience. Master’s degree (MS) with 1-2 years of relevant work experience. Doctorate degree (PhD) with no experience
• Ability to communicate verbally and in writing at all levels inside and outside the organization
• Basic familiarity with Microsoft Office Suite
• Computer skills, commensurate with Essential Functions, including the ability to learn a validated system
• Able to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts Sometimes on short notice
• Able to work under specific time constraints
• Must be authorized to work in the United States without a sponsor visa, now or in the future

Pay

The pay rate for this role is $80k/year.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years. We’re committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.

Equal Employment Opportunity

Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws. It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications. For more information, please visit www.criver.com.