Senior Associate Scientist

Genentech’s Analytical Operations (AO) department is seeking an enthusiastic and motivated Associate Scientist to join our analytical testing team. This role utilizes analytical tools to characterize the physical and chemical properties of biopharmaceutical products, supporting process development, validation, and product quality, purity, and stability assessments. This position is based in South San Francisco, on site.

About Analytical Operations (AO)

Analytical Operations (AO) is a non-GMP department within the PTDA Analytical Development Quality Control organization, dedicated to advancing the company's R&D pipeline. The department provides technical expertise and analytical support for early-stage research, development, and process validation across the South San Francisco campus and other Genentech/Roche sites. Support is delivered through high-throughput testing, automation, effective data management, and robust business processes to facilitate timely and scientifically informed decisions.

Responsibilities

• Conduct routine and non-routine analytical testing using a variety of physiochemical techniques (U/HPLC, iCIEF, CE-SDS, LC-MS, and Karl Fischer), according to established protocols.
• Maintain accurate, detailed documentation of assays and data results in an Electronic Laboratory Notebook (ELN), strictly adhering to ALCOA+ principles.
• Perform essential lab support tasks, including stocking consumables, checking for expired reagents and hazardous waste, and de-icing freezers.
• Comply with laboratory best practices, safety guidelines, and internal and regulatory standards.

Requirements

• Bachelor’s degree with a minimum of 3 years of relevant experience, or a Master’s degree with laboratory experience in Chemistry, Biochemistry, or a related scientific field. Experience in the biotech or pharmaceutical industry is preferred.
• Hands-on experience with HPLC/UPLC, CE, or LC-MS is required.
• Must be highly organized, detail-oriented, and self-motivated, with a proven ability to manage multiple tasks both independently and collaboratively.
• Strong written and verbal communication skills, with the ability to present technical work clearly.
• Knowledge of GMP compliance, experience with ELN, and intermediate proficiency in Microsoft Excel is highly desirable.
• Ability to lift up to 20 lbs for laboratory-related tasks.

Pay

The expected salary range for this position based on California is $92,600 - $172,000 USD annually. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

Benefits

This position qualifies for Genentech’s comprehensive benefits program, including health, retirement, and wellness offerings.