Senior Associate Scientist

RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals.

About the role

RayzeBio is looking for a Senior Associate Scientist to support the development of novel therapeutics in preclinical stages. Candidates will work as part of a team of scientists to synthesize and design both small molecules and peptide analogs to optimize potency, pharmacokinetics, and in vivo efficacy of potential drug candidates. This position offers a challenging and rewarding work environment within a thriving company.

Responsibilities

• Executing multi-step synthetic routes, optimizing reaction conditions, isolation, and characterization of organic compounds (chromatography, NMR, MS, IR spectroscopy).
• Collaborating effectively with colleagues across diverse disciplines.
• Documenting research activities and presenting findings clearly.
• Executing experimental plans, troubleshooting synthetic challenges, and contributing to the optimization of lead compounds.

Requirements

• BS or MS in Chemistry with strong demonstrable expertise in synthetic organic and medicinal chemistry.
• 3+ years experience (BS) or 2+ years (MS) in a non-academic synthetic chemistry laboratory.

Skills

• Strong small molecule synthetic skills and knowledge of laboratory techniques and safety, with experience synthesizing peptides a plus.
• Proficiency in compound synthesis techniques, reactions, compound purification, troubleshooting, and characterization using methods such as LCMS, HPLC, and NMR.
• Familiarity with scientific software such as ChemDraw, Scifinder, and Reaxys.
• Adaptable and flexible, able to handle multiple demands and shifting priorities.
• Self-motivated with good interpersonal skills and ability to work effectively in a fast-paced, collaborative environment.
• Adept in documenting and presenting findings clearly through laboratory notebook, reports, and presentations.
• Uses AI tools to enhance individual productivity and quality of work.

Physical Demands

• Regularly required to sit, reach with hands and arms, and talk or hear.
• Must occasionally lift and/or move up to 40 pounds.
• Specific vision abilities required include close vision and distance vision.
• Requires working in a laboratory environment; protective clothing, gloves, and safety glasses are required while working with radioactive materials.

Work Environment

The noise level in the work environment is usually moderate.

Pay

San Diego - RayzeBio - CA: $95,505 - $115,730 (full-time employee basis). Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life Benefits:
  • Paid Time Off (US Exempt Employees): Flexible time off (unlimited, with manager approval), 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico, or RayzeBio employees).
  • Phoenix, AZ, Puerto Rico, and RayzeBio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays.
  • Based on eligibility, additional time off may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs, and an annual Global Shutdown between Christmas and New Year's Day.

All global employees (full and part-time) who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.