Senior Associate Scientist

About the role

Biomedicine Design’s Endogenous Antibody Discovery Group is seeking a Senior Associate Scientist (contingent worker) to support antibody discovery projects focused on B cell-based workflows. This role contributes to therapeutic antibody discovery campaigns through rodent immunization, serum titer screening, B cell sorting by flow cytometry, immune library generation, and hybridoma-based methods.

Responsibilities

• Provide laboratory support for therapeutic antibody discovery campaigns using flow cytometry, immune library generation, and hybridoma-based methods.
• Execute established workflows to support rodent immunization studies, serum titer screening, B cell sorting, molecular cloning, and related sample processing activities.
• Support antibody discovery workflows involving rodent selection and immunization strategies, including protein, cell-based, and genetic immunization approaches.
• Perform serum response evaluation using ELISA and support flow cytometry-based applications.
• Conduct VH/VL molecular cloning, immune library generation, quality control activities, electrofusion, and hybridoma culture and screening processes.
• Maintain reagent inventories, prepare laboratory materials, and ensure operational readiness for discovery activities.
• Accurately document experimental procedures, observations, and results in laboratory records and internal data systems.
• Organize experimental data and communicate findings, campaign progress, and outcomes to project teams.
• Participate in the evaluation and implementation of technologies that improve immunization and flow cytometry-based antibody discovery workflows.
• Collaborate effectively with team members to support project objectives and laboratory operations.

Requirements

The candidate should have a Bachelor’s degree in Biology, Immunology, Molecular Biology, Biochemistry, or a related scientific discipline, and a minimum of 2 years of full-time laboratory experience in an academic or industry setting. Hands-on experience supporting antibody discovery workflows, including flow cytometry, B cell-based methods, or hybridoma-based screening, is required.

Skills

• Hands-on experience supporting antibody discovery workflows.
• Knowledge of flow cytometry and B cell-based methods.
• Experience with hybridoma-based screening workflows.
• Working knowledge of molecular biology techniques, including PCR and cloning.
• Experience with immune library generation or related sample preparation workflows.
• Ability to accurately document laboratory procedures, experimental results, and observations.
• Strong data organization and communication skills.
• Strong laboratory organization skills, including reagent handling and inventory management.
• Ability to maintain laboratory materials and support operational readiness for experimental workflows.

Preferred Skills

• Experience with flow cytometry-based analysis or cell sorting.
• Experience with laboratory automation or high-throughput workflows.
• Experience working with rodents, particularly mice, in a research setting.
• Experience with hybridoma generation, culture, or screening workflows.

Pay

The typical base pay for this role across the U.S. is $40.42 - $41.33/hr. Non-exempt positions are eligible for overtime at a rate of 1.5 times the base hourly rate for all hours worked in excess of 40 in a work week, or as required by state or local law.

Benefits

Full-time employees are eligible to select from different benefits packages, which may include medical, dental, and vision benefits, health savings accounts with qualified medical plan enrollment, 10 paid days off, 3 days paid bereavement leave, 401(k) plan participation with employer match, life and disability insurance, commuter benefits, dependent care flexible spending account, accident insurance, critical illness insurance, hospital indemnity insurance, accommodations and reimbursement for work travel, and discretionary performance or recognition bonus. Sick leave and mobile phone reimbursement provided based on state or local law.