SD Scientist I

About the role

This position offers an exciting opportunity to work with new non-viral nucleic acid delivery tools for in vivo and ex vivo genome editing and gene therapy applications. The role involves the analysis of novel nanoparticle-based pharmaceuticals.

Responsibilities

• Work at the direction of Analytical scientists to quantitate lipid nanoparticles (LNPs) encapsulating nucleic acids
• Analyze raw materials for LNP formulations
• Establish relationships between physiochemical characteristics of experimental nanoparticle formulations and their efficacy and safety
• Maintain detailed records of analytical data
• Interface directly with other functional teams
• Share responsibility for basic lab management activities (supply ordering, instrument calibration, maintaining schedules)

Requirements

• Master's or Bachelor's degree with 2+ years' experience in pharmaceutical sciences, bioengineering, chemical engineering, chemistry, or related scientific discipline (an equivalent combination of education and experience may be considered)
• Practical experience using analytical methods such as RiboGreen, Dynamic Light Scattering (DLS), and Zeta potential measurement is strongly preferred
• Prior experience with High-Performance Liquid Chromatography (HPLC) is preferred
• Experience and proficiency with other analytical techniques will be considered
• Proficiency at formulating buffers is required
• Excellent attention to detail and ability to produce consistent results and effectively communicate them to the team
• Ability to be a team player, multitask and work on multiple projects at once, and excel in a collaborative work environment
• Proficiency at MS Excel is required; prior experience with advanced analytical software (Prism, JMP) is desirable
• Excellent oral and written communication skills

Work Location: San Diego, CA
Duration: Long Term