Scientist/Sr. Scientist - Electrophysiology

Responsibilities

• Execution of electrophysiological studies:
• Devise assays to isolate and measure biophysical parameters related to activity of various ion channel targets (Cl-, Na+, Ca+, K+).
• Design, set up, and maintenance of electrophysiology equipment and peripheral hardware for custom-built fast perfusion for ligand and/or drug application according to assay needs.
• Carry out manual patch-clamp (voltage-clamp) recordings of ligand-gated, and/or voltage-gated, ion channels to allow for pharmacological and drug-interaction kinetic analysis.
• Data analysis and presentation:
• Analyze, quality control, and present electrophysiological data to internal stakeholders and external clients.
• Prepare study plans and study reports.
• Engage with electrophysiology team members, and other PsychoGenics teams, as well as external clients on study design and progress.

Qualifications

• PhD in Neuroscience (or cardiovascular, muscle, or related field), with minimum 5 years' experience in study of ligand-gated and/or voltage-gated ion channel biophysics.
• Ability to independently lead set-up, configuration, and maintenance of electrophysiology rig hardware, including customized fast-application system for delivery of ligand/drug to cells.
• Highly skilled in manual patch-clamp of cells in culture in whole-cell configuration (experience with excised patch highly desired).
• C competence in electrophysiology software acquisition, and strong data analysis skills (skills in computational tools like R and/or Python highly desired).
• High level of commitment to quality, organizational ability to simultaneously work on multiple projects, and strong motivation to perform and provide deliverables on tight timelines to internal stakeholders and external clients.
• Effective communication skills, and data presentation skills to internal stakeholders and external clients.
• Collegial team member, and adept at working in a matrixed work environment with cross-funcational teams.
• Experience with preparation of acute rodent brain slices or other tissues for patch-clamp electrophysiology; multi-electrode array electrophysiology experimental set-up and data analysis is a BIG PLUS.

Total Rewards Plan

• Total Rewards Plan details provided in the Benefits section.

Benefits

• Medical, dental, vision and life insurance plans
• HSA, FSA and dependent FSA
• Short- and long-term disability plans
• Stock-based incentive plan
• 401K with company contribution
• Tuition reimbursement
• Generous paid time off policy and paid parental leave policy
• EAP
• Additional voluntary benefits

Pay

Competitive performance-based compensation, discretionary bonus for both individual and PsychoGenics annual performance.

Schedule

Flexible schedule to accommodate the needs of the position and the client.