Scientist / Senior Scientist, Metabolomics Group Lead

Responsibilities

• Collaborate with cross-functional scientists to define project objectives, assess feasibility, and establish clear deliverables and timelines
• Execute and supervise sample preparation workflows for steady-state metabolomics and lipidomics
• Operate, maintain, and troubleshoot LC-MS instrumentation (e.g., Thermo Exploris 240, SCIEX 7500, Vanquish HPLC) to ensure optimal performance and minimal downtime
• Optimize and adapt extraction protocols to support analysis of diverse and challenging biological samples
• Process and analyze raw datasets with software (e.g. Skyline, Compound Discoverer), and coordinate with bioinformatics teams to ensure accurate data processing, quality control, and efficient project execution
• Maintain accurate and up-to-date project tracking and documentation in systems, such as Benchling, and shared project management tools
• Communicate project status, timelines, and risks effectively to internal stakeholders and leadership

Requirements

• PhD (or equivalent experience) in metabolomics, lipidomics, analytical chemistry, biochemistry, or a related discipline.
• 6 years of hands-on experience with both HRAM and LRMS preferably with Orbitrap Exploris and SCIEX triple quadrupole mass spectrometry platforms.
• Strong experimental design and problem-solving skills, with experience performing sample preparation of cells, tissues, and biofluids.
• Demonstrated experience with mentoring and project management, including managing collaborations with scientists with diverse training backgrounds.

Qualifications

• Experience developing new methods for analysis of metabolites/lipids of interest
• Prior experience in Metabolite Identification and trapping in the context of drug metabolism
• Experience performing large-scale discovery studies of > 1,000 samples
• Experience designing and interpreting complex isotope tracing experiments (e.g., metabolic flux analysis)
• Experience integrating metabolomics/lipidomics with other omics, including proteomics and transcriptomics

Skills

Not specified

Benefits

Not specified

Pay

Redwood City, California Scientist II: $156,800- $201,000
Senior Scientist : $172,400- $221,000

Schedule

Not specified