Scientist, Quantitative Systems Pharmacology

About the role

The Quantitative Systems Pharmacology (QSP) group of Sanofi is seeking to hire a highly talented modeling scientist to support its portfolio in early clinical development. The QSP group is part of Translational Informatics department within the Translational Medicine and Early Development organization of Sanofi. The individual will primarily be involved with hands-on quantitative systems pharmacology modeling activities, and he/she will be responsible to work with internal and external collaborators to ensure alignment with the strategic needs of the project team. The position will be based in Morristown, NJ.

Main responsibilities

• Function as part of a team to develop and apply multiscale computational models of complex diseases based on detailed biological mechanistic knowledge to support model-informed drug discovery & development.
• Survey literature to gain understanding of critical physiological processes to be represented, and identify suitable mechanistic elements, data, parameters and assumptions to be included.
• Identify and analyze suitable internal preclinical and clinical data to inform modeling activities.
• Analyze simulation results and identify appropriate strategies to resolve issues pertaining to model performance and accuracy.
• Maintain extensive documentation of model development process, and data analysis.
• Maintain quantitative systems pharmacology expertise through comprehensive education.
• Communicate modeling predictions to key stakeholders.

About You

• PhD in systems pharmacology/biology, computational biology, biomedical engineering, or a related field with a strong record of productivity demonstrated through publications and scientific presentations with at least 2 years of Postdoctoral experience in disease modeling/QSP.
• Masters degree with 4+ years of relevant industry experience.
• Proficiency in mathematical modeling using differential equations.
• Extensive experience in computational tools such as MATLAB, Julia and R (MATLAB preferred).

Desirable Qualifications

• Experience in drug discovery/development a plus, especially in bioinformatics or pharmacometrics.
• Knowledge of Immunology.

Soft Skills

• Excellent oral and written communication skills.
• Ability to quickly learn pathophysiology in indications of interest, and treatment approaches in immunology.
• Highly motivated, detail-oriented, and independent researcher.
• Able to thrive in a collaborative, multi-disciplinary team environment.
• Strong commitment to on-the-job-training.

Why Choose Us

• Pursue Progress. Discover Extraordinary.
• Better is out there. Better medications, better outcomes, better science.
• We are an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth.
• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.