Jobs · Research · California

Scientist Protein Engineering Organic Chemist: ADC Research & Development

BioSpace · Thousand Oaks, CA · 3 wk ago
ResearchFull-time

Key Responsibilities

  • Design, synthesize, purify, and characterize linker/payloads for antibody-drug conjugates (ADCs).
  • Design and generate ADCs, including conjugation, purification, and characterization to support therapeutic discovery.
  • Analyze and interpret data, and communicate results through clear documentation, reports, and project updates.

Qualifications

  • Doctorate degree
  • OR Masters degree and 2 years of organic chemistry and laboratory experience
  • OR Bachelors degree and 4 years of organic chemistry and laboratory experience

Preferred Qualifications:

  • Strong proficiency in organic synthesis and chemical methodology development
  • Knowledge of, or experience with, protein conjugation and protein chemistry techniques
  • A robust understanding of structural determination using NMR and MS, with proficiency in chromatographic techniques (e.g., HPLC, RP-HPLC, ion exchange, and size-exclusion chromatography)
  • Demonstration of good lab practices, with particular attention to safety
  • Strong written and verbal communication skills
  • Ability to work comfortably within a team of scientists and engineers with diverse technical and cultural backgrounds.

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