Scientist - Non-Viral Gene Delivery
About the role
Merge Labs is a frontier research lab with the mission of bridging biological and artificial intelligence to maximize human ability, agency and experience. We’re pursuing this goal by developing fundamentally new approaches to brain-computer interfaces that interact with the brain at high bandwidth, integrate with advanced AI, and are ultimately safe and accessible for anyone to use.
The Delivery team develops the viral and non-viral delivery technologies that enable Merge's next-generation neurotechnology platform. By partnering closely with bioengineering, neuroscience, and in vivo teams, we create delivery systems that support rapid preclinical testing while advancing the platform toward safe and effective human translation. We work across disciplines to come up with creative ideas and solve some of the most challenging problems in biotechnology.
As a Scientist in the Delivery team, you will develop and evaluate non-viral gene delivery approaches that enable the expression and function of novel molecular biosensors and actuators of neural activity in preclinical models. Your work will serve as the critical bridge between molecular engineering and in vivo functionality and enable the ultimate clinical translation of molecular BCI. You will collaborate closely with protein engineers, cell and synthetic biologists, data scientists, physicists and neurobiologists.
Responsibilities
- Identify the best non-viral delivery technologies wherever they exist and help to secure access through collaborations, material transfer agreements, or in-licensing.
- Work hands-on in our lab to formulate, adapt, and characterize LNPs, polymeric nanoparticles, and other non-viral vehicles for delivery of nucleic acid payloads to the central nervous system.