Scientist, Molecular Interactions, Discovery Biologics

About the role

We are seeking a highly motivated Scientist to join the Molecular Interactions team within Early Biologics Characterization at Discovery Biologics in Boston. In this hands-on laboratory role, you will apply a range of biosensor and biochemical technologies to characterize protein therapeutics and their targets, generating critical data that drives biologics discovery and candidate selection.

We are looking for a passionate and collaborative scientist with a strong sense of curiosity, a desire to solve challenging scientific problems, and a commitment to generating high-quality data. Join a team where innovation, scientific rigor, and cutting-edge technologies come together to advance the next generation of biologic medicines.

Responsibilities

• Execute and optimize fit-for-purpose binding assays to evaluate affinity, kinetics, epitope specificity, cross-reactivity, and molecular quality of biologic therapeutics
• Perform protein conjugation
• Conduct biophysical characterization studies
• Implement new technologies
• Communicate results to cross-functional project teams

Qualifications

• Bachelor's degree in Biomedical Sciences, Biochemistry, Bioengineering, Molecular Biology, or a related discipline with 2 years of postgraduate hands-on relevant laboratory experience OR Master's degree with 1+ year of hands-on relevant laboratory experience
• Hands-on experience executing SPR and BLI based assays on biosensor platforms including Carterra, Biacore, or Octet
• Understanding of protein-protein interaction analysis, including binding affinity, kinetics, and data interpretation
• Experience using scientific data analysis tools such as GraphPad Prism, Microsoft Excel, or equivalent software
• Demonstrated ability to execute experiments, analyze and interpret data, troubleshoot technical challenges, and communicate results effectively
• Strong organizational skills with the ability to manage multiple assignments in a dynamic, team-oriented environment
• Effective written and verbal communication skills

Preferred Qualifications

• Experience developing or optimizing assays using ELISA, Microscale Thermophoresis (MST), KinExA, or related technologies
• Experience with protein conjugation techniques
• Experience with automated liquid-handling systems
• Experience using flow cytometry or FACS
• Experience supporting biologics discovery, protein sciences, or therapeutic characterization programs

Required Skills

• Automated Liquid Handling Systems
• Biologics
• Biophysical Characterization
• Detail-Oriented
• Enzyme Linked Immunosorbent Assay (ELISA)
• High-Throughput Screening
• Surface Plasmon Resonance (SPR)
• Therapeutic Proteins

Preferred Skills

• Cell Cultures
• Flow Cytometry
• Protein Purifications

Pay

The salary range for this role is $98,000.00 - $154,300.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

Benefits

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.