Jobs · Analyst · Pennsylvania

Principal Scientist, Biologics Discovery

Johnson & Johnson Innovative Medicine · Spring House, PA · 2 wk ago
On-siteAnalystFull-time

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

About the Role

This position is dedicated to advancing the discovery and development of innovative biotherapeutics targeting unmet medical needs through immune-mediated approaches. As a key contributor, you will leverage your expertise in Immunobiology and T-cell biology to support portfolio programs and drive the success of discovery initiatives.

Responsibilities

  • Leading or actively participating in project teams to progress discovery portfolio projects.
  • Driving technology development efforts for multispecific antibody platforms and validating readiness for portfolio inclusion.
  • Designing, conducting, and interpreting in vitro immune cell functional assays and related experimental studies.
  • Presenting and defending scientific findings independently within multidisciplinary teams and initiatives.
  • Authoring patent applications, manuscripts, study protocols, SOPs, and technical reports.
  • Managing and mentoring scientific staff.

Requirements

  • Ph.D. degree in life sciences (molecular biology, biochemistry, immunology, or a related discipline) with 4+ years post-doctoral experience OR Master’s Degree in life sciences with at least 6+ years of experience.
  • Extensive understanding of immunology, including in vitro and in vivo models relevant to immuno-oncology and autoimmune disease.
  • Demonstrated experience with immune cell-based assays such as multi-color flow cytometry, cytotoxicity, and multiplex cytokine assays.
  • Experience developing novel, complex, and high-throughput immune assays for functional characterization and MOA studies.
  • Ability to work effectively in a matrixed environment—both within the group and across the broader organization.
  • Strong dedication, motivation, and a collaborative approach to advancing therapeutic innovation.
  • Commitment to continuous learning and scientific excellence.
  • Excellent analytical and problem-solving skills for experimental design and data interpretation.
  • Exceptional communication skills, with the ability to present complex data clearly and concisely.

Preferred Qualifications

  • Experience in end-to-end drug development processes.
  • Industry experience.

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