Scientist, In Vivo CAR-T
BioSpace · Somerset, NJ · 3 days ago
On-siteOTHR$96k–$126k/yrFull-time
Key Responsibilities
- Develop and optimize cell-based assays to support cell therapy programs.
- Perform immune cell isolation, activation, expansion, and T cell culture.
- Conduct lentiviral vector packaging, titration, and transduction experiments.
- Execute assays including multi-color flow cytometry, ELISA, cytotoxicity assays, and PCR.
- Design and carry out experiments with moderate independence; analyze and interpret data.
- Document experimental results clearly and present findings to team members.
- Collaborate with cross-functional teams to evaluate constructs and generate reproducible data.
- Support progression of research programs from discovery toward early development.
- Maintain awareness of emerging technologies and scientific advancements.
- Provide general laboratory support as needed.
- Work closely with internal research teams and cross-functional partners (e.g., development, manufacturing).
- Contribute to team discussions, troubleshooting, and project execution.
Requirements
- PhD in Immunology, Cell Biology, Molecular Biology, or a related field.
- OR Master’s degree with 3–6+ years of relevant experience.
- Hands-on experience in immunology, cell therapy, gene therapy, or related fields.
- Experience with viral vector systems (especially lentivirus) is highly preferred.
- Industry or postdoctoral experience is a plus.
- Cell biology and molecular biology techniques.
- Virology and viral vector systems (e.g., lentivirus).
- Mammalian cell culture and immune cell handling.
- Flow cytometry and immunoassays.
- Strong data analysis, organization, and problem-solving skills.
- Ability to work both independently and collaboratively.