Jobs · OTHR · New Jersey

Scientist, In Vivo CAR-T

BioSpace · Somerset, NJ · 3 days ago
On-siteOTHR$96k–$126k/yrFull-time

Key Responsibilities

  • Develop and optimize cell-based assays to support cell therapy programs.
  • Perform immune cell isolation, activation, expansion, and T cell culture.
  • Conduct lentiviral vector packaging, titration, and transduction experiments.
  • Execute assays including multi-color flow cytometry, ELISA, cytotoxicity assays, and PCR.
  • Design and carry out experiments with moderate independence; analyze and interpret data.
  • Document experimental results clearly and present findings to team members.
  • Collaborate with cross-functional teams to evaluate constructs and generate reproducible data.
  • Support progression of research programs from discovery toward early development.
  • Maintain awareness of emerging technologies and scientific advancements.
  • Provide general laboratory support as needed.
  • Work closely with internal research teams and cross-functional partners (e.g., development, manufacturing).
  • Contribute to team discussions, troubleshooting, and project execution.

    Requirements

    • PhD in Immunology, Cell Biology, Molecular Biology, or a related field.
    • OR Master’s degree with 3–6+ years of relevant experience.
    • Hands-on experience in immunology, cell therapy, gene therapy, or related fields.
    • Experience with viral vector systems (especially lentivirus) is highly preferred.
    • Industry or postdoctoral experience is a plus.
    • Cell biology and molecular biology techniques.
    • Virology and viral vector systems (e.g., lentivirus).
    • Mammalian cell culture and immune cell handling.
    • Flow cytometry and immunoassays.
    • Strong data analysis, organization, and problem-solving skills.
    • Ability to work both independently and collaboratively.

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