Scientist, Exploratory Technology in vivo CAR-T

Key Responsibilities

• Produce research grade lentivirus to perform exploratory research.
• Perform lentivirus titering such as p24 ELISA and qPCR.
• Contribute in developing and optimizing novel cell and gene therapy platforms and in vitro cell-based immunoassays such as whole blood transduction.
• Setup in vitro CAR T cell culture, characterization and functional assays including PBMC culture, T cell isolation and expansion, multi-color flow cytometry, cytotoxic assays (e.g. IncuCyte), cytokine detection (e.g. MSD) and VCN analysis.
• Independently design and execute experiments and at the same time, work closely with the team and cross-functional teams in a highly collaborative environment.
• Deliver reliable and consistent data and be able to interpret scientific results and present the data within research team and cross-functional teams.
• Complete ELN in a timely manner with good documentation skills.
• Support laboratory chores as a good team player.

Requirements

• PhD in Immunology, Cell Biology, Molecular Biology, or a related field OR Master’s degree with 3–6+ years of relevant experience.
• Hands-on experience in immunology, cell therapy, gene therapy, or related fields.
• Experience with viral vector systems (especially lentivirus) is highly preferred.
• Industry or postdoctoral experience is a plus.
• Cell biology and molecular biology techniques.
• Virology and viral vector systems (e.g., lentivirus).
• Mammalian cell culture and immune cell handling.
• Flow cytometry and immunoassays.
• Strong data analysis, organization, and problem-solving skills.
• Ability to work both independently and collaboratively.