Scientist, Immuno-Oncology

About the role

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development.

Responsibilities

• Design, execute, and analyze cellular and immunological assays supporting antibody and multi-specific therapeutic programs
• Perform mammalian cell culture, immune cell isolation, immune phenotyping, and functional characterization assays
• Support sample preparation and execution of microscopy-based experiments, including fluorescence imaging and other advanced imaging platforms
• Aid in the development, optimization, and troubleshooting of in vitro assays for therapeutic molecule evaluation
• Generate, analyze, and interpret experimental data using appropriate statistical and visualization tools
• Present findings at internal team meetings and contribute to scientific discussions
• Maintain detailed laboratory records and prepare written summaries of experimental results
• Collaborate closely with scientists across immunology, protein engineering, bioassays, and computational biology teams
• Contribute to the establishment of new experimental methods and workflows as programs evolve
• Other duties as assigned

Qualifications

• PhD in Immunology, Cell Biology, Cancer Biology, Molecular Biology, Bioengineering, or a related field
• Strong hands-on experience with mammalian cell culture and cell-based assays
• Working knowledge of immunology and immune cell biology
• Experience with fluorescence microscopy, image analysis, or sample preparation for imaging applications is highly desirable
• Experience with flow cytometry, immune phenotyping, or functional immune assays preferred
• Demonstrated ability to learn new technologies and experimental techniques quickly
• Strong analytical, organizational, and problem-solving skills
• Excellent written and verbal communication skills
• Collaborative mindset with a positive, adaptable, and proactive approach to research
• Possess the right attitude (agile, curious, positive, open-minded, “can-do” mindset), and have the ability and strong desire to “make things happen”