Scientist, Immune Engineering
AstraZeneca · Waltham, MA · 2 wk ago
Analyst$91k–$137k/yrFull-time
About the role
We are seeking an early-career Scientist to join the Cellular Resilience team to contribute to groundbreaking, early discovery research at the intersection of gene delivery and cell therapy. The successful candidate will leverage their expertise in immune cell engineering, functional assay development, and synthetic/molecular biology to develop the next generation of cellular therapies.
Responsibilities
- Engineer cell lines and primary immune cells by viral and non-viral techniques
- Develop in-vitro cellular assays with an emphasis on high-throughput readouts such as multicolor flow cytometry, plate reader, ELISA/MSD, qPCR
- Analyze and interpret complex experimental data, present findings to both internal and external stakeholders
Qualifications
- BS/MS with 5+ years or PhD with 0+ years of post-graduate experience in a relevant field including (but not limited to) molecular biology, synthetic biology, immunology, biological/chemical/biomedical engineering
- Hands-on experience in the culture and engineering of established cell lines and primary human immune cells by viral and non-viral techniques such as lentivirus, AAV, LNP, electroporation
- Hands-on experience with the execution and data analysis of immune functional assays including in vitro cytotoxicity, co-cultures, proliferation, and cytokine measurement
- Proactive, highly self-motivated, and thrives in a workplace where goals may shift
Preferred Qualifications
- Experience with multi-color flow cytometry experiment design, acquisition, and analysis
- Experience with gene editing technologies (e.g., CRISPR, TALE, Zinc Finger) and evaluating gene editing outcomes (e.g., flow cytometry, qPCR, Sanger sequencing, NGS)
Benefits
- Competitive total reward program including a market-driven base salary, bonus, and long-term incentive
- Generous paid time off program and comprehensive benefits package
- Qualified retirement programs
- Health, dental, and vision coverage
Pay
The annual base pay for this position ranges from $91,008.80 to $136,513.20. Positions offer eligibility for various incentives, including short-term incentive bonuses, equity-based awards for salaried roles, and commissions for sales roles.
Posted: 10-Aug-2026 | Closes: 30-Aug-2026