Scientist II/III, LCMS Method Development

About the Role

Pharmaron is seeking a Scientist II/III, LCMS Method Development to join our growing Bioanalytical Sciences team in Exton, PA. In this role, you will contribute to the development and validation of innovative bioanalytical methods supporting drug discovery and development programs across a diverse range of therapeutic modalities, including small molecules, peptides, oligonucleotides, PROTACs, biologics, and emerging therapies.

Responsibilities

• Independently develop, optimize, validate, and troubleshoot LC-MS/MS bioanalytical methods.
• Design scientifically sound studies that meet sponsor and internal objectives.
• Execute and support bioanalytical testing for DMPK and regulated studies.
• Perform sample analysis using HPLC and LC-MS/MS platforms in compliance with developmental and GLP requirements.
• Review and execute study protocols governing bioanalytical studies and sample analysis.
• Process, analyze, interpret, and report study data.
• Author protocols, validation reports, technical summaries, and study reports.
• Support regulatory submissions through high-quality scientific documentation.
• Serve as Principal Investigator (PI) and/or Study Director (SD) within areas of expertise.
• Actively identify and resolve technical challenges while driving continuous improvement.
• Collaborate with scientists, project teams, management, business development, and clients to ensure successful project execution.
• Participate in project review meetings and compliance-related initiatives.

Requirements

• Bachelor's degree in Pharmaceutical Sciences, Chemistry, Life Sciences, or a related scientific discipline.
• Scientist II: Minimum 2 years of bioanalytical testing experience.
• Scientist III: Minimum 4 years of bioanalytical testing experience.
• Experience supporting development and/or GLP-regulated bioanalytical studies.
• Strong understanding of HPLC and LC-MS/MS methodologies.
• Excellent analytical thinking, troubleshooting, and organizational skills.
• Ability to thrive in a fast-paced, collaborative, and matrixed environment.

Qualifications

• Experience with LC-MS/MS method development and validation (preferred).
• Experience analyzing peptides, oligonucleotides, PROTACs, and complex biologics (preferred).
• Familiarity with DMPK studies and regulated bioanalysis (preferred).
• Experience authoring scientific reports and supporting regulatory submissions (preferred).
• Prior CRO, pharmaceutical, or biotechnology industry experience (preferred).
• Experience serving in client-facing scientific roles (preferred).

About Pharmaron

Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the US, UK, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services. We're proud of the impact we make and just last year, we supported 887 discovery projects, 1,100+ CMC programs, and 1,397 clinical trials across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers.

Why Pharmaron?

Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities. Our collaborative culture fosters an inclusive and innovative environment where teamwork and individual contributions make a real impact. We offer a comprehensive benefits package, including medical, dental, and vision insurance, a 401(k) retirement plan, generous paid time off, and professional development opportunities.

Benefits

• Comprehensive Medical, Dental & Vision Insurance with significant employer contributions
• 401(k) Retirement Plan with generous employer matching
• Generous Paid Time Off (PTO), Paid Sick Leave & Company Holidays
• Employer-funded Health Savings Account (HSA) contributions (for eligible plans)
• Healthcare & Dependent Care Flexible Spending Accounts
• 100% Employer-paid Employee Life Insurance, AD&D, Short- and Long-Term Disability Insurance
• Employee Assistance Program (EAP), mental health resources, and wellness programs
• Family-friendly benefits, including fertility support and maternity resources
• Professional development and career growth opportunities

Salary Range: $65,000-$85,000
Location: Exton, PA (On-site)