LCMS Scientist
Eurofins DiscoverX · St Charles, MO · 1 mo ago
On-siteScienceFull-time
About the role
Eurofins Scientific is an international life sciences company providing analytical testing services across industries to ensure product safety, authenticity, and compliance. The Scientist I – Analytical Chemist will support Eurofins Discovery’s contract research services, focusing on ADME Toxicology Services and related assays, with responsibilities including LC-MS method development, troubleshooting, and data quality assurance.
Responsibilities
- Perform laboratory work, including production assays in ADME Toxicology Services and other services such as BioMAP®, Immunosignaling, Ion Channel, and/or OncoPanel™ based on business needs.
- Develop Liquid Chromatography-Mass Spectrometry (LC-MS) methods for ADME/DMPK applications.
- Develop analytical methods to support project teams internally and externally for new assay development.
- Troubleshoot and maintain mass spectrometers and HPLC units; experience with Sciex® or Waters instrumentation is a plus.
- Prepare and manage inventory of buffers, reagents, semi-finished, and finished goods.
- Provide solutions to complex problems and identify process improvements.
- Maintain high data quality and reproducibility; perform data and report QC review within the department, and may support the study director.
- Take ownership of client projects with minimal supervision.
- Support validation of new methods and contribute to the expansion of service/product lines, equipment, and data management systems.
- Understand and comply with GxP requirements; complete required training and support 100% of Employee Health and Safety requirements.
- Demonstrate proficiency in the care and maintenance of lab equipment and department assets.
- Adhere to department SOPs and documentation requirements; maintain accurate data management and reporting.
- Support unit goals and demonstrate Eurofins’ competencies as defined in the job plan.
- Provide training to colleagues and external end users when required.
- Contribute to scientific community, site research, and development objectives.
- Work effectively in a team environment under minimal direction to achieve business production, project timelines, and quality objectives.
- Adjust work hours and provide cross-functional support to other departments as required, maintaining accountability for client needs and timelines.
- Routinely communicate project updates to internal and external clients.
Qualifications
- Education: B.S. with minimum 5 years relevant laboratory experience; M.S. with minimum 3 years; Ph.D. with minimum 1 year; or equivalent education and experience.
- Work Requirements:
- Direct experience with LC-MS or LC-UV in a CRO or industry laboratory for ADME/DMPK applications.
- Experience working in a Quality Management System.
- Scientific expertise with mass spectrometry-based quantification for ADME/DMPK applications in biological matrices.
- Experience with analytical method development and optimization.
- Familiarity with validation of bioanalytical methods per FDA, ICH guidelines.
- Experience with liquid handling, automation, solid-phase extraction (SPE), HTS applications, and large-scale screening.
- Experience in small team leadership and project management.
- Experience leading and delivering results in R&D or innovation programs.
- Authorization to work in the United States indefinitely without restriction or sponsorship.
Ideal Candidate
- Good communication and interpersonal skills.
- Demonstrated proficiency contributing independently on project teams with timely, quality deliverables.
- Ability to read, write, and interpret documents such as SOPs and technical reports.
- Ability to perform mathematical calculations, statistical analyses, and data interpretation.
- Ability to multitask with organization and manage time effectively.
- Ability to solve practical problems and troubleshoot effectively.
- Ability to work in a laboratory setting according to physical requirements.
- Proficiency with lab equipment and office computer/software.
- Above-average oral and written communication skills.
- Positive attitude, capacity for teamwork, and genuine interest in drug discovery supporting human health.
- Ability to develop new methods and lead research and development projects.
- Ability to review and QC release data/reports.
- Ability to lead small, informal sub-teams, train, and onboard new team members.
- Ability to conduct mid-size projects with minimal supervision.
- Ability to contribute to strategic vision, establishment of new service lines, equipment, and data management systems.
- Ability to support cross-functional demands.
Schedule
Full-time position with schedule Sunday–Thursday or Saturday–Wednesday, 8:00 PM–5:00 PM.
Candidates living within a commutable distance of St. Charles, MO are encouraged to apply.
Benefits
- Comprehensive medical, dental, and vision coverage.
- Life and disability insurance.
- 401(k) with company match.
- Paid vacation and holidays.