Scientist, II

Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube. Job Description AbbViesGastrointestinal(GI)/Immunology Discovery Research group is looking for a highly motivated andexperienced invivo and in vitropharmacologistto play an integral role inadvancing therapeuticsto treat inflammatory GI disorders.This position offers an exciting opportunity tounderstand thepharmacodynamic effectsof experimental medicineswith GI relevant in vitro and in vivo assays. The ideal candidate would work within the highly matrixed and collaborativeDiscovery Immunologyteam toguidetest articlescreening and assay development as well asbuild biology packages forearly stageprograms.Experimental focus will be ondeveloping andleveragingin vivo and in vitro systems tohelpunderstand the impact of test articlesinmucosal immunity.The candidate is expected to design, execute,interpretand present innovative research to advance programstowards the clinic.We are seeking a hands-on experimentalist who isproficientwithin vivo and in vitrocell biology research andhasdemonstratedscientificleadership withinternal and externalstake holders/experts.The expectation is that the candidate would dedicatethe majority oftheir time toward wet lab experimentation, dataanalysisand presentation.In addition, we are seeking a candidatewith excellent written and oral communication skills.The candidate will have the opportunity to present their results at team and internal/external science meetings.Priortechnicalexperience inIBDmouse models, humanized mice,biologicsmolecule screening, and handling of human tissuearerequired. Major Responsibilities Highly autonomous and productive in performing laboratory research and method development, requiring only minimal direction from supervisor Execute ondiscovery screening funnels fornovel test articles Design, execute and analyze in vivopharmacologystudies in colitis or other GI mouse models Prepareand execute experiments withhuman blood or intestinal tissue Formulate conclusions and design follow-on experiments based on multidisciplinary data Primary author of regulatory documents. Understand and adhere to corporate standardsregardingcode of conduct, safety,appropriate handlingof materials, controlled drug and radioactive compounds, and animal care