Scientist I - Single-cell Genomics and Bioinformatics

About the role

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

Responsibilities

• Support initiatives across the Allen Institute for Brain Science, Allen Institute for Neural Dynamics and Allen Institute for Immunology to create reference atlases for cells in the peripheral nervous system using single-cell genomic data
• Apply and adapt existing computational and experimental approaches to integrate gene expression and epigenetic information from a variety of single-cell genomic datasets
• Collaborate with team members to interpret biological findings from data and contribute ideas for follow-up experiments, gaining independence and autonomy over time
• Learn and apply analytical methods for defining cell types and predicting enhancer activity from single-cell data and for supporting the development of genetic tools that mark distinct functional or anatomical cell types
• Contribute to computational method development for single-cell genomics, under the guidance of team leads
• Present research findings regularly to internal team members and stakeholders; contribute to the preparation of manuscripts, grant proposals, and external presentations

Requirements

• Ph.D. in Bioinformatics, Genomics, Neuroscience or related field; or equivalent combination of degree and experience
• Demonstrated experience with single-cell genomics analysis or large-scale data analysis
• Proficiency in programming languages and tools (R, Python, cloud computing)
• Proficiency in AI tool use, and interest in AI tool development

Preferred

• Experience in reproducibly analyzing large single-cell and spatial genomics (transcriptomics, epigenomics, proteomics) datasets
• Experience integrating spatial data with single-cell genomics approaches
• Ability to work independently and within a collaborative, multi-disciplinary environment to meet demanding timelines
• Positive attitude, self-motivated, and demonstrated ability to creatively troubleshoot
• Proven strong publication record
• Knowledge of mouse molecular genetics, neuroscience, and neuroanatomy
• Exceptional oral and written communication and organizational skills

Physical Demands

Fine motor movements in fingers/hands to operate computers and other office equipment

Position Type/Expected Hours of Work

This role is currently able to work both remotely and onsite in a hybrid work environment. We are a Washington State employer, and the primary work location for all Allen Institute employees is 615 Westlake Ave N.; any remote work must be performed in Washington State.

Travel

Attendance and participation in national and international conferences is required

Annualized Salary Range

$86,500 - $106,100

Benefits

Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institutes Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institutes 401k plan. Paid time off is also available as outlined in the Allen Institutes Benefits Guide. Details on the Allen Institutes benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits.

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform essential functions.