Scientist I – Fischer Lab

Responsibilities

• Independently plan and perform purification strategies for recombinant proteins and protein complexes from insect, mammalian or bacterial cells.
• Structure determination by cryo-EM
• Responsible for supporting the needs of multiple small molecule discovery projects.
• Responsible for preparing and delivering scientific presentations as needed.
• Takes a lead role in the biochemistry, structural biology of projects.
• Train lab members in sample preparation, image acquisition and data processing for cryoEM and negative stain.
• Thoroughly documents all experiments, results and findings in a laboratory notebook.

Qualifications

• PhD degree in biochemistry, structural biology or a related discipline with at least 2 years of relevant postdoctoral experience.
• Must have experience in experimental and computational cryo-EM techniques.
• Must possess excellent communication and presentation skills.
• Proven track record of publications in peer reviewed journals reflecting scientific drive.
• Ability to collect and analyze experimental data, prepare research publications and communicate results.
• Demonstrated ability to work in a fast-paced and dynamic environment.
• Ability to work independently as well as in a collaborative and team environment.
• Strong experience in protein biochemistry, protein purification and biophysical characterization.
• Familiarity with biophysical techniques used to assess interactions between proteins and proteins with small molecules.
• Experience in recombinant protein expression in bacterial, insect and/or mammalian cells.
• Experience with purification of recombinant proteins and protein complexes.

Benefits

The Fischer Lab at Dana-Farber Cancer Institute offers a competitive compensation package including a salary range of $80,000.00 - $95,900.00 per year.

Pay

The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.

Schedule

Onsite: 100% onsite