Scientist I Biopreservation

Duties And Responsibilities

• Design and conduct experiments to evaluate Biopreservation strategies including cryopreservation, freezing, thawing and cold-chain storage workflows for mammalian cells and cellular therapeutics.
• Develop and optimize biopreservation formulations and protocols for immune cells, stem cells, and other therapeutic cell types and tissues.
• Perform and interpret assays including: Flow cytometry, cell viability and apoptosis assays, metabolic and functional assays, and post-thaw recovery kinetics.
• Analyze experimental data and generate reports to guide protocol optimization.
• Collaborate with cross-functional teams including scientific applications, product development and external clients and collaborators.
• Contribute to technical reports, presentations, publications and white papers.
• Participate in interactions with partners and customers evaluating biopreservation methods, including attending seminars and conferences.

Job Requirements

• Deep understanding of the principles of cryopreservation, freeze-thaw processes and cold-chain.
• Hands-on experience in and demonstrated ability to troubleshoot both adherent and in-suspension mammalian cell cultures.
• Fluency and experience in designing and troubleshooting cell-based assays and analytical techniques including fluorescent imaging techniques, flow cytometry and ICS, ELISAs.
• Strong skills in experiment design and DOE, data analysis and statistics, and scientific writing.
• Training or research experience in Biopreservation methods, including cryobiology, vitrification methods, lyophilization and cellular stabilization.
• Familiar with and demonstrated ability to apply GLP for lab work documentation.
• Demonstrated ability to publish scientific work and skills for presentations at conferences.
• Familiarity with process development concepts relevant to CGT manufacturing.
• Demonstrated initiative to advance the field by generating innovative ideas and proposing solutions to key challenges in biopreservation and CGT/RMM.
• Maintain scientific leadership by actively monitoring and studying emerging research and major developments in the field.
• Strong communication and collaboration skills.
• Attention to detail and careful documentation.
• Passion for translating fundamental science into real-world therapeutic impact.