Jobs · Research · California

Scientist

CHEManager International · Hayward, CA · 5 days ago
Research$80k–$110k/yrFull-time

About the role

We are seeking a highly motivated and experienced Scientist specializing in LC-MS/MS to join our dynamic team. This individual will play a pivotal role in quantitative bioanalysis and the characterization and identification of drug metabolites, contributing to our understanding of DMPK (Drug Metabolism and Pharmacokinetics) and its impact on drug safety and efficacy.

Responsibilities

  • Develop and optimize sample preparation and analytical methodology for quantitative measurement of drugs in a variety of modalities and metabolite profiling/identification using state-of-the-art LC-MS/MS and high-resolution mass spectrometry (HRMS).
  • Lead and execute LC-MS/MS-based projects in a timely and high-quality manner.
  • Interact with clients to provide actionable insights on method development and sample analysis-related challenges.
  • Operate, maintain, and troubleshoot LC-MS/MS instruments; serve as instrument lead as needed.
  • Prepare and review scientific reports, presentations, and regulatory documents to ensure accuracy and compliance with industry standards.
  • Stay updated on advancements in LC-MS/MS technologies and methodologies.
  • Collaborate with cross-functional teams and provide technical guidance when needed.
  • Mentor and train junior lab staff.

Requirements

  • Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field.
  • Solid hands-on experience with LC-MS/MS-based bioanalytical method development including sample preparation, instrument operation, and data processing.
  • Proven track record operating LC-MS/MS systems in a bioanalytical lab.
  • Strong expertise in drug metabolism and biotransformation, with hands-on experience in metabolite identification using LC-MS/MS and HRMS.
  • Demonstrated ability to analyze and interpret complex mass spectrometry data and provide detailed reports.
  • Excellent communication skills and ability to work both independently and collaboratively in a cross-functional team environment.
  • Experience in pharma or biotech environment is a plus.

Benefits

  • Health and dental insurance
  • 401(k) plan
  • Health insurance
  • Short and long-term disability insurance
  • Life insurance

Pay

Salary Range: $80,000 to $110,000

Location: Hayward, CA
Reports To: Director

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