Scientist, Analytical Development & Quality Control

Key Responsibilities

• Analytical Development
• Independently develop, optimize, and validate analytical methods for characterizing and quantifying plasmids, IVT impurities, RNA drug substances, lipids, and small molecules.
• Utilize techniques including CGE, LC-UV/MS, LC-CAD, qPCR, and ELISA.
• Troubleshoot analytical methods and instrumentation issues.
• Quality Control
• Conduct and interpret QC testing to support Process Development and Formulation teams by assessing materials for in vitro and in vivo studies.
• Data Analysis & Reporting
• Analyze and interpret experimental data; effectively communicate findings to cross-functional teams.
• Contribute to troubleshooting and continuous improvement of analytical methods and workflows.
• Documentation
• Maintain accurate and detailed laboratory records.
• Author and review SOPs, analytical methods, and qualification/validation reports to facilitate QC transfer.
• Cross-Functional Collaboration
• Collaborate with Discovery, Process Development, and formulation teams to support research and development efforts.

Qualifications

• Proven experience in developing and validating quantitative analytical methods for RNA and small molecules.
• Extensive experience with analytical techniques such as Capillary Gel Electrophoresis (CGE), qPCR, HPLC (CAD/UV), and Mass Spectrometry preferred.
• Additional experience with Nanopore and ELISA techniques is a plus.
• Strong analytical thinking and problem-solving skills.
• Excellent communication and technical writing abilities.
• Ability to excel in a fast-paced startup environment.
• Self-motivated, adaptable, and eager to learn.

Education & Experience

• Ph.D. in Analytical Chemistry, Biochemistry, or related field with 1–3 years of industry experience.
• Master’s with 6-8 years. OR Bachelor’s with 9 -10 years

Compensation

The expected hourly rate for this position is $111,000-$140,000. Exact compensation may vary based on skills and experience.