Scientist 1, Oligonucleotide Chemist (Synthesis & Purification)

About the role

BioMarin is seeking a dedicated and skilled Scientist specializing in oligonucleotide synthesis to contribute to our cutting-edge research and development efforts in nucleic acid-based therapeutics. This role offers a unique opportunity to be part of a dynamic team at the forefront of biotechnology innovation, working on projects that have the potential to transform patient outcomes.

Key Responsibilities

• Engage actively in project team discussions across the organization, providing subject matter expertise to support the progression of research projects and the development of new methodologies.
• Work synergistically with multidisciplinary teams, including bioconjugation specialists, chemists, and biologists, to drive project success and foster a collaborative research environment.
• Execute oligonucleotide synthesis utilizing automated solid-phase synthesis methodologies to ensure high-quality and reproducibility of synthesized oligonucleotides.
• Conduct purification of synthesized oligonucleotides via high-performance liquid chromatography (HPLC) and other relevant techniques to achieve the desired purity and quality standards.
• Maintain comprehensive and meticulous records of experimental protocols, results, and data analyses, ensuring data integrity and compliance with regulatory standards.
• Contribute to the maintenance of a safe and compliant working environment, adhering to all health and safety regulations and promoting a culture of safety within the laboratory.

Education & Requirements

• PhD degree in Chemistry with 0-2 years of industry experience or Master’s degree with 8-10 years in the biotech or pharmaceutical industry.

Skills

• Demonstrated ability to work independently as well as part of a collaborative team environment, with a proactive approach to problem-solving and advancing research programs.
• Strong enthusiasm for scientific research and innovation, coupled with excellent organizational skills and the ability to manage multiple tasks and projects simultaneously.
• Commitment to maintaining up-to-date knowledge of advancements in oligonucleotide chemistry and related fields, with a willingness to engage in ongoing professional development.
• Expertise in solid-phase oligonucleotide synthesis and purification, with a strong track record of successful project outcomes.
• Excellent written and verbal communication skills, with the ability to effectively present data and findings to both technical and non-technical audiences.

Work Style

This is an onsite daily role in San Rafael, CA. This role will have a daily presence in our Research labs executing experiments. This position represents an exciting opportunity to contribute to BioMarin's mission of developing innovative therapies for patients with serious and life-threatening conditions. We look forward to welcoming a passionate and skilled oligonucleotide chemist to our team.