Jobs · Analyst · California

Scientific - Scientist II

Select Source International · Sunnyvale, CA · 4 wk ago
On-siteAnalystFull-time

About the role

We are seeking an experienced Scientist to support the development, optimization, and integration of automated molecular biology workflows for next-generation sequencing (NGS) applications. This is a hands-on laboratory position focused on nucleic acid sample processing, NGS library preparation, workflow automation, and experimental optimization. The ideal candidate is a self-motivated experimentalist who can independently design and execute laboratory experiments, troubleshoot complex molecular biology workflows, analyze results, and collaborate with multidisciplinary teams to advance automated sample-to-library preparation processes.

Responsibilities

  • Execute and optimize automated workflows for nucleic acid extraction, amplification, and NGS library preparation.
  • Develop and evaluate automated sample preparation and sequencing library construction workflows.
  • Design, perform, analyze, and document experiments to assess workflow performance, robustness, and reproducibility.
  • Troubleshoot molecular biology processes integrated with automated fluidic and consumable platforms.
  • Perform DNA/RNA quantification, library QC, normalization, pooling, and sequencing preparation.
  • Operate and troubleshoot laboratory automation platforms and associated laboratory instrumentation.
  • Analyze experimental data and communicate findings to project teams and leadership.
  • Collaborate with teams across assay development, automation engineering, bioinformatics, consumables development, and systems engineering.
  • Prepare detailed experimental reports, protocols, procedures, and technical documentation.
  • Support technology transfer, verification, and validation activities as projects progress.
  • Maintain accurate laboratory records and follow established laboratory practices and safety procedures.
  • Identify opportunities for continuous improvement of automated workflows and laboratory processes.

Requirements

  • Bachelor s or Master s degree in Molecular Biology, Genetics, Biochemistry, Biotechnology, Microbiology, or a related scientific discipline.
  • 3 5 years of relevant laboratory experience in molecular biology, genomics, or a related field.
  • Demonstrated hands-on experience with NGS library preparation workflows.
  • Experience operating and troubleshooting laboratory automation platforms.
  • Experience integrating molecular biology processes into automated or semi-automated workflows.
  • Strong understanding of PCR, DNA extraction, nucleic acid quantification, and sequencing library QC.
  • Experience with genomics instrumentation and relevant analytical software.
  • Strong experimental design, data analysis, documentation, and communication skills.
  • Ability to independently plan and execute laboratory experiments with minimal supervision.

Qualifications

  • Experience developing or optimizing workflows within cartridge-based or consumable-based automated systems.
  • Experience with Illumina, Oxford Nanopore, or other NGS technologies.
  • Familiarity with automated magnetic bead purification and nucleic acid cleanup workflows.
  • Experience supporting product development, verification, or validation activities.
  • Knowledge of assay development principles and sequencing workflow optimization.
  • Experience working with biological samples.
  • Experience working in a cross-functional product development environment.
  • Exposure to NGS data analysis or bioinformatics workflows.

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