Research Technician III

Job Duties

• Independently manage day-to-day laboratory operations, including inventory tracking, procurement of supplies, and maintenance of laboratory organization and safety compliance.
• Oversee rodent colony management, including breeding strategies, genotyping, health monitoring, and compliance with institutional animal care protocols.
• Perform and optimize biochemical and molecular assays (e.g., protein analysis, histology), ensuring high reproducibility and data integrity.
• Diagnose and troubleshoot experimental and technical issues, including assay variability, equipment malfunction, and protocol deviations.
• Maintain detailed experimental records, analyze data trends, and communicate findings to laboratory personnel.
• Provide technical guidance and training to students, trainees, and junior staff on laboratory methods and best practices.
• Independently harvest and process tissues using sterile and reproducible techniques, ensuring sample integrity for downstream analysis.
• Design, coordinate, and execute multi-day experimental workflows assessing skeletal muscle function, including:
• Day 1: Measurement of contractile properties (e.g., force generation, fatigue resistance) using specialized muscle physiology equipment.
• Day 2: Quantitative assessment of intracellular calcium dynamics and reactive oxygen species (ROS) using fluorescence microscopy and imaging-based assays.
• Care for and operate, calibrate, and maintain specialized instrumentation (e.g., muscle physiology rigs, fluorescence microscopes), ensuring optimal performance and reliability.
• Develop and refine imaging and functional assay protocols to improve sensitivity, throughput, and reproducibility.
• Analyze complex datasets derived from functional and imaging experiments and prepare summaries for presentation and publication.
• Identify and implement technical improvements to increase efficiency and consistency in experimental workflows.

Requirements

• Bachelor's degree in a Basic Science or related field.
• Four years of related experience may substitute for degree requirement.
• One year of relevant experience.

Preferred Qualifications

• Master's degree in basic science or a related field.
• One year of animal handling preferred.