Research Scientist, Inflammatory Bowel Disease (IBD) Drug Discovery

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description: Objective / Purpose : The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs. We seek a Research Scientist to join our biology and cross-functional discovery teams and create novel drug candidates. Your role provides technical leadership for research project implementation and coordination,begins at the conception of new projects and helps advance to candidate selection,generates exciting and rigorous data that drive confident decisions,contributes critical thinking, technical expertise, and scientific insight to teamwork, andmaintains our Takeda culture that promotes creativity, open communication, cooperation, and urgency while delivering the highest quality of science for drug discovery. Accountabilities : Identify, plan, and execute well-defined scientific projectsInitiate investigation of new experimental approaches to specific problems using scientific theory and technical literatureUse defined practices and theoretical knowledge to perform analyses, interpret results, and determine appropriate actionsUtilize relevant information, technology, and resources to proactively contribute to solving complex problems and achieving objectives as a teamPrepare and present comprehensive project and technical reports to a range of internal and external audiences Education & Competencies (Technical and Behavioral) : PhD degree in a scientific discipline (or equivalent), or MS with 6+ years relevant experience, or BS with 8+ years relevant experienceDemonstrated accomplishments in inflammation and/or immunology research, with a track record of applying scientific insight to address complex biological questions; experience in inflammatory bowel disease is a plusStrong expertise in molecular biology, cell biology, and immunology, with experience developing cell-based and biochemical assaysHands-on experience with key technologies including flow cytometry, primary human immune cell and fibroblast culture, cytokine analysis (AlphaLISA, MSD, ELISA), qPCR, and gene editing approaches (e.g., CRISPR, siRNA)Experience developing in vitro assays to characterize small and large molecules for potency and mechanism of actionExperience contributing to the design and execution of in vivo efficacy, pharmacology, and MoA studies in rodent modelsAbility to independently design and execute experiments while contributing effectively within a collaborative, matrixed team environmentStrong problem-solving skills with the ability to generate high-quality data and derive insights that inform project decisionsExcellent written and verbal communication skills and the ability to work effectively in a highly matrixed environmentStrong organizational and multi-tasking skills with attention to detail Takeda Compensation and Benefits Summary: We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: USA - MA - Cambridge - Binney St U.S. Base Salary Range : $116,000.00 - $182,270.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement: Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations: USA - MA - Cambridge - Binney St Worker Type: Employee Worker Sub-Type: Regular Time Type: Full time Job Exempt: Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.