Research Scientist I - Zhu Lab

Position Summary

The Zhu Lab at the Versiti Blood Research Institute focuses on unraveling the mechanisms of receptor transmembrane signaling, particularly on cell surface receptors like integrins, receptor tyrosine kinases, and receptor-like tyrosine phosphatases. Using a multidisciplinary approach involving structural biology, protein engineering, biochemistry, and cell biology, the lab aims to understand how these receptors transmit signals across the cell membrane. Current projects include studying bi-directional transmembrane signaling in integrins, elucidating integrins as pathogen receptors, exploring integrin ligand interactions, and developing inhibitors targeting specific integrin conformations. Additionally, the lab investigates the mechanism behind coronavirus spike protein-mediated cell fusion and viral infection, with a goal to develop antiviral treatments and diverse virus-based applications.

Responsibilities

• Takes direction from the Principal Investigator (PI) to design and execute goal-oriented, hypothesis-driven research programs.
• Applies for local and national grants to fund relevant research.
• Conducts experimental work and data analyses.
• Maintains an active scientific publication and presentation record, contributing to the lab's research goals.
• Provides direction and/or supervises research technologists, pre- and postdoctoral trainees.
• Participates actively in the scientific community within the Blood Research Institute.
• Performs other duties as required or assigned.

Qualifications

• PhD, MD, or equivalent degree in a related scientific area required.
• Minimum of 1-3 years of postdoctoral experience required.
• Demonstrated ability to independently apply scientific theory to research experiments.
• Ability to interpret and explain the theoretical basis of the work performed.
• Proven ability to perform research procedures independently.
• Immediate proficiency in basic and advanced laboratory tests and procedures.
• Exceptional organizational, communication, and problem-solving skills.
• Strong detail orientation and analytical abilities.
• Ability to prioritize and manage multiple tasks and meet deadlines.
• Experience in supervising and coordinating the work of several individuals involved in a project.