Research Scientist (Basic Life Research Scientist) 1 Year Fixed-Term

Qualifications

• Ph.D. in Immunology, Cell Biology, Bioengineering, Molecular Biology, or a related field
• At least 3 years of relevant postdoctoral or equivalent research experience in academia or industry
• Demonstrated ability to independently design and execute complex biological experiments
• Strong background in T cell immunology, including CAR/TCR engineering and cytokine signaling
• Experience with in vivo mouse tumor models, including adoptive cell therapy approaches
• Experience with flow cytometry (multicolor panels, intracellular staining, phospho-flow)
• Experience with primary immune cell culture, including T cell isolation, activation, and genetic engineering (e.g., lentiviral transduction)
• Familiarity with molecular biology techniques (PCR, cloning, vector design)
• Experience managing or supporting a mouse colony, including breeding and genotyping workflows
• Ability to work independently while contributing effectively in a collaborative research environment
• Strong organizational and project management skills, with the ability to manage multiple concurrent projects
• Excellent written and verbal communication skills

Core Duties

• Lead and execute independent research projects focused on T cell engineering, cytokine signaling, and cancer immunotherapy
• Design and perform complex experiments spanning in vitro systems and in vivo mouse models, including tumor implantation, adoptive T cell transfer, and therapeutic studies
• Develop and optimize experimental strategies to evaluate CAR/TCR function and cytokine signaling in immune cells
• Analyze and interpret complex datasets (e.g., flow cytometry, in vivo tumor response, functional assays) and use findings to refine research direction
• Manage and maintain a complex laboratory mouse colony, including designing breeding strategies, overseeing genotyping, and ensuring timely availability of experimental animals
• Establish and implement new experimental approaches where existing methods are insufficient, particularly for engineered signaling systems
• Collaborate with lab members and external partners to coordinate experiments and advance multidisciplinary projects
• Contribute to manuscript preparation, figure generation, and presentation of research findings at internal and external venues
• Mentor and train junior lab members in experimental techniques, particularly in vivo models and cellular immunology workflows
• Ensure compliance with institutional and federal regulations, including animal protocols (APLAC/IACUC) and laboratory safety standards