Research Manager D, Rodent Metabolic Phenotyping Core

The University of Pennsylvania, a world-renowned leader in education, research, and innovation, is the largest private employer in Philadelphia. Consistently ranked among the top 10 universities in the U.S. News & World Report survey, Penn offers a unique working environment within the city of Philadelphia, combining a beautiful urban campus with easy access to educational, cultural, and recreational activities.

About the Role

Serve as Research Manager of the Institute for Diabetes, Obesity, and Metabolism’s Rodent Metabolic Phenotyping Core. Provide daily management for all activities in the Rodent Phenotyping Core, including training and supervising research specialists and technicians. Design and perform metabolic studies in mouse models, chemical and immunoassays on tissues, analyze assay results, and communicate findings to investigators. Maintain core usage statistics, collaborate with the Core director for long-range planning, develop and monitor lab safety guidelines, manage the service center budget, and oversee lab facilities and supplies.

Responsibilities

• Take primary responsibility for strategic planning and day-to-day management of core staff performing complex in vivo studies in rodent models for core clients, including labs within and outside the University of Pennsylvania.
• Train and supervise Research Specialists and Technicians, serving as the liaison between the director, core clients, and staff.
• Develop protocols, ensure proper technique execution, manage equipment and data collection systems, and ensure data analysis follows accepted practices.
• Establish expertise in technical and theoretical aspects of core assays, including metabolic clamps, indirect calorimetry, telemetry, bomb calorimetry, DEXA, EchoMRI, and other services as needed.
• Plan and manage the service center budget, including evaluating and setting prices, projecting future revenue and expenses, and collaborating with multiple client labs.
• Order and manage lab supplies and coordinate rodent transfers to ensure all necessary resources are available for core experiments.
• Prepare financial, regulatory, and technical progress reports for the Core Director, Penn IDOM, NIH, and other agencies.
• Maintain core usage data for reporting purposes.
• Assist with drafting grants and/or articles for publication.
• Directly perform and analyze assays in rodent models, including:
  • Body composition (NMR; DEXA)
  • CLAMS
  • Treadmill exercise insulin/glucose clamp and radioisotopic tracer kinetics
  • Thermography
  • BAT thermogenesis
  • Tissue chemistry
  • ELISA
  • Glucose and insulin tolerance tests
• Interface with companies and Penn IT to troubleshoot equipment and software issues, ensuring smooth core operations.
• Perform additional duties as needed to support animal research on campus, including consulting with internal and external investigators on experimental design and approaches.

Requirements

• Bachelor of Science/Arts and 5 to 7 years of experience, or an equivalent combination of education and experience, is required.
• Master's degree or PhD preferred.

Benefits

• Health, Life, and Flexible Spending Accounts: Comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits. Flexible spending accounts for eligible health care and dependent care expenses with pre-tax dollars.
• Tuition Assistance: Exceptional tuition benefits for employees, spouses, and dependent children at Penn and other institutions.
• Retirement Plans: Generous retirement plans allowing pre-tax or Roth savings with a variety of investment options through TIAA and Vanguard.
• Time Away from Work: Substantial paid time off for vacations, personal affairs, illness, or injury.
• Long-Term Care Insurance: Coverage for long-term care services at home, in the community, or in a nursing facility for employees and eligible family members.
• Wellness and Work-life Resources: Programs and resources to support health, family, and work-life balance.
• Professional and Personal Development: Resources to advance personal and professional growth.
• University Resources: Access to libraries, athletic facilities, arboretum, art galleries, and cultural and recreational activities.
• Discounts and Special Services: Discounts on arts, entertainment, transportation, mortgages, cellular phone service plans, movie tickets, and theme parks.
• Flexible Work Hours: Creative approaches to work hours, locations, and job structures to promote work-life balance.
• Penn Home Ownership Services: Forgivable loans for eligible employees buying a home or residing in West Philadelphia.
• Adoption Assistance: Reimbursement for qualified expenses related to the legal adoption of an eligible child.

Pay

$80,891.00 - $100,000.00 Annual Rate. Salary offers are based on the candidate’s qualifications, experience, skills, and education as they relate to the position, and are aligned with external market and internal peer data.

Job Location: Philadelphia, Pennsylvania