Research Lab Ops Manager Microscopy Core

About the role

Performs a variety of research and research administration activities in direct support of the Department's research faculty and programs. Responsible for managing the overall functioning of the research operation. Serves as a front-line resource for researchers in the Department, acting as liaison to internal administrative units and external sponsors on matters relating to research programs.

Responsibilities

• Oversight of all lab supply and equipment, purchasing and maintenance.
• Congnrols all regulatory and compliance activities.
• Trains staff in specialized lab techniques.
• Assists with subject scheduling.
• Provides input on strategy, based on knowledge of industry and trends.
• Applies project management techniques to ensure development initiatives stay on track.
• Contributes to scientific literature and may present the data at meetings.
• Carries out independent research projects which involve the execution of highly sophisticated techniques.

Qualifications

• Bachelor's Degree in a related field of study required or Master's Degree in a related field of study preferred.
• Experience in research (in a lab setting) 3-5 years required.

Skills and Abilities

• Independent decision-making in appropriate situations.
• Scientific imagination commensurate with the independent execution of research projects.
• Aptitude for technical problem solving.
• Excellent organizational skills to ensure smooth functioning of lab.
• Demonstrated analytical skills and ability to logically sequence experiments to maximize research.
• Aptitude for budget management.

Specialized Duties

• Maintain the Reichert-Jung ultramicrotome and ancillary TEM instrumentation.
• Oversee and maintain the JEOL JEM1200EX TEM and cooling systems.
• Conduct TEM for MRC and external investigators, including: resin sample preparation, ultramicrotomy, staining, data collection, and image processing.
• Immuno-electron microscopy techniques.
• Cryo-preservation and freeze substitution of samples.
• Electron tomography on ultrathin sections and tomogram reconstruction.
• Negative staining for specific biological samples.
• Prepare sample supports (Formvar and carbon-coated grids, glow discharge, addition of gold fiducials).
• Train users on independent operation and image processing tools for the confocal microscope.
• Perform confocal microscopy for MRC and external investigators.
• Maintain the Leica SP8-TCS LSCM in optimal condition.
• Train users on the two-photon microscope and associated image processing tools.
• Provide technical guidance and assistance for two-photon microscopy.
• Maintain the two-photon microscope in optimal condition.
• Implement and manage a structured user sign-up system for all instruments.
• Ensure compliance with all lab safety, security, and hazardous waste disposal regulations.
• Maintain an adequate inventory of lab consumables and essential supplies.
• Generate and issue monthly usage invoices for all Core instruments and services.
• Prepare and manage the annual budget for Core expenses.
• Keep detailed and accurate records of all financial transactions associated with the Core facility.

Pay

$63,252.80 - $102,596.00/Annual

Schedule

Day (United States of America)