Research Lab Manager 2

About the role

The Carvill Lab in the Department of Neurology is seeking a new Lab Manager to join our team. Our research focuses on the genetic and epigenetic basis of epilepsy; we use numerous genomic technologies as well as iPSCs to study pathogenic mechanisms towards discovering new precision therapies.

Responsibilities

• Manages daily operations of a research lab.
• Maintains lab performance, analyzes and reviews results, and supervises development and implementation of new protocols.
• Sets and oversees work assignments for lab personnel and ensures technical operations are quality controlled and functioning up to standards.
• Develops, implements, and administers budgets, grant and administrative procedures.
• Co-authors scientific papers for presentation and publication and coordinates writing, submission and administration of grants.
• Manages technical operations of a lab involved in scientific research activities.
• In consultation with Principle Investigator (PI) organizes and plans experiments ensuring those project objectives are attained.
• Oversees and guides lab staff in review of results and recommendation of changes to protocols to improve validity and accuracy.
• Conducts more complex experiments and analysis.
• Using an advanced level of skill, completes the following activities:
  • Molecular Biology: DNA, RNA, Protein isolation, purification and expression; Southern, Northern, Western blotting; PCR, RT-PCR; Plasmid preparation; Cloning, mapping and sequencing of DNA; Recombinant virus production and purification.
  • Cellular Biology: Cell culture, cell isolation; Functional studies; Transfection; Histology: Tissue fixation/processing: embedding, preparation of blocks and sectioning, staining; Immunohistochemistry; Microscopy; Immunology: Flow cytometry; ELISA, Elispot assay; Cytokine assay; Antibody production and purification.
  • Animal Husbandry: Breeding and screening transgenic mice; Dissections; Blood collection; Surgical procedures.
  • Database management of colony; Administration; Oversees and manages collection, maintenance, analysis and evaluation of data that will be used in grant submissions, presentations and publications.
  • Ensures that information is entered correctly into databases.
  • Aids PI in reviewing, analyzing, interpreting, summarizing, formatting, editing, and preparing tables, charts, graphs, progress and final reports, etc.
  • Collaborates with sponsoring agencies, collaboration organizations and/or other research and/or educational institutions.
  • Ensures research regulations are adhered to, IRB and ACUC approvals in place, material transfer agreements properly executed, and that radiation and lab safety requirements are up to date and implemented.
  • Manages lab budget and inventory including purchasing of supplies and services ensuring that they are necessary, reasonable and project related.
  • Orders and maintains inventory of lab supplies, chemicals, equipment and instrumentation and may distribute intra-departmental charges.
  • Negotiates with vendors, obtain quotes and arrange for demos of large equipment.
  • Trains, directs, assigns duties to & supervises lab EEs, students, residents &/or fellows.
  • Provides instruction to lab users on technically complex procedures, equipment & instruments.
  • Typically manages a lab budget of $1,000,000-$3,000,000; 1,000 - 3,000 nasf of space & supervises 5-15 lab members.

Qualifications

• Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelor's or higher degree in a scientific major or related; OR appropriate combination of education and experience and 6 years' lab/bench or other relevant experience required; OR Successful completion of a full course of study in an accredited college or university leading to a master's or higher degree in a scientific major or related; OR appropriate combination of education and experience and 4 years' lab/bench or other relevant experience.
• Supervisory or project management experience required.

Benefits

At Northwestern, we are proud to provide meaningful and competitive benefits. The available benefits package for this position will include health, dental, vision, disability, and life insurance; paid vacation and holidays; paid medical/sick and parental leave; tuition benefits for the employee and dependents; pre-tax and flex spending accounts for commuting and dependent care; generous retirement savings options; and wellness programs. For a comprehensive overview of available benefits, including eligibility details, visit us at https://www.northwestern.edu/hr/benefits/index.html.

Work-Life And Wellness

Northwestern offers comprehensive programs and services to help you and your family navigate life’s challenges and opportunities, and adopt and maintain healthy lifestyles. We support flexible work arrangements where possible and programs to help you locate and pay for quality, affordable childcare and senior/adult care. Visit us at https://www.northwestern.edu/hr/benefits/work-life/index.html to learn more.

Professional Growth & Development

Northwestern supports employee career development in all circumstances whether your workspace is on campus or at home. If you’re interested in developing your professional potential or continuing your formal education, we offer a variety of tools and resources. Visit us at https://www.northwestern.edu/hr/learning/index.html to learn more.