Research Associate, Systems Integration
Element Biosciences · San Diego, CA · 4 days ago
Analyst$69k–$85k/yrFull-time
About the role
We are seeking an experienced Research Associate, Systems Integration to support the development, optimization, and integration of molecular biology workflows for next-generation life science products.
Responsibilities
- Execute molecular biology and biochemical assays to support product integration, workflow optimization, and performance testing
- Perform nucleic acid and protein-related laboratory techniques, including DNA/RNA handling, buffer preparation, reagent formulation, enzymatic reactions, hybridization-based assays, amplification workflows, and NGS-based readouts
- Prepare, process, and analyze biological samples such as cultured cells, fixed cells, tissue sections, or other relevant sample types
- Support assay optimization by testing protocol variables such as reagent concentrations, incubation times, temperature conditions, wash conditions, sample preparation steps, and workflow timing
- Generate high-quality experimental data and evaluate assay performance using metrics such as signal intensity, background, reproducibility, specificity, sensitivity, sample quality, and workflow robustness
- Operate and maintain common laboratory equipment such as pipettes, centrifuges, thermocyclers, plate readers, fluorescence microscopes, incubators, biosafety cabinets, and next generation sequencers where applicable
- Assist with troubleshooting assay failures, reagent issues, sample variability, workflow inconsistencies, and instrument-related observations
- Maintain accurate and complete experimental records, including electronic lab notebook entries, protocols, data files, analysis summaries, and technical reports
- Collaborate with scientists, engineers, manufacturing, quality, applications, and product development teams to support product readiness, protocol transfer, and workflow reliability
- Support verification, validation, and design transfer activities by executing structured test plans and documenting results according to internal standards
- Help maintain an organized, safe, and compliant laboratory environment, including inventory tracking, reagent labeling, sample management, and adherence to safety procedures
Requirements
- Bachelor's or Master's degree in molecular biology, biochemistry, bioengineering, biology, genetics, cell biology, biomedical engineering, or a related scientific field
- 1-3+ years of relevant laboratory experience for Research Associate level; additional industry experience may be considered for a more senior level
- Hands-on experience with core molecular biology techniques, including DNA/RNA handling, pipetting, reagent preparation, enzymatic assays, amplification reactions, and sequencing
- Experience working with biological samples such as cultured cells, fixed cells, tissue sections, or extracted nucleic acids and proteins
- Strong laboratory technique, attention to detail, and ability to execute complex multistep protocols reproducibly
- Experience analyzing and organizing experimental data using tools such as Excel, JMP, ImageJ/Fiji, or similar software
- Able to recognize technical issues, communicate observations clearly, and contribute to structured troubleshooting
- Strong written and verbal communication skills, including the ability to document experiments clearly and present results to cross-functional teams
- Able to work independently while contributing effectively in a collaborative, fast-paced product development environment
Qualifications
- Preferred experience with one or more of the following: fluorescence microscopy, immunofluorescence, in situ hybridization, PCR/qPCR, NGS library preparation, oligo handling, protein detection assays, tissue processing, or assay development
- Preferred experience in biotechnology, life science tools, diagnostics, genomics, sequencing, imaging, or product development environments
Physical Requirements
- Must be able to remain in a stationary position for extended periods while performing benchwork or data analysis
- Frequently moves laboratory supplies, reagent containers, sample boxes, or equipment weighing up to 20 pounds
- Must be able to perform repetitive fine-motor tasks such as pipetting, tube handling, slide handling, and sample preparation
- Must be able to work safely with standard molecular biology reagents, biological samples, and laboratory chemicals in accordance with established safety protocols