Research Associate - RNA Synthesis Platform Development

Are you passionate about advancing RNA therapeutics and cutting-edge biotechnology? We're seeking a talented Research Associate to join our dynamic team in Waltham, where innovation meets impact in the rapidly evolving world of mRNA technology. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Qualifications

• Bachelor's degree in Biochemistry, Molecular Biology, Chemical Engineering, or related field.
• 1+ years of hands-on experience in an industrial laboratory setting.

Skills

Technical Expertise

• Biochemistry Foundation: Strong background in enzymatic reactions and catalysis, with particular emphasis on in vitro transcription (IVT) reactions and enzyme kinetics.
• RNA Biochemistry: Demonstrated expertise in RNA synthesis, protein and nucleic acid biochemistry, and enzymatic process development (preferably in mRNA manufacturing).
• Laboratory Automation: Experience with Hamilton Vantage automated systems and Venus software for liquid handling methods.
• Analytical Techniques: Proficiency in RNA purification and characterization assays including Ethanol precipitation, Spectrophotometry, Capillary electrophoresis, ELISA, and qPCR methodologies.
• Scientific Rigor: Strong experimental design skills and quantitative data analysis capabilities.

Language & Soft Skills

• Fluency in English (written and verbal).
• Detail-oriented with excellent organizational skills.
• Collaborative mindset with strong communication abilities.
• Adaptability in a fast-paced, innovative environment.

Responsibilities

• Drive Platform Innovation: Support individual program development through the application of cutting-edge platform synthesis technologies.
• Technology Development: Evaluate and develop new technologies for improving current platform processes, pushing the boundaries of what's possible in RNA synthesis.
• Automated Systems Management: Operate and optimize Hamilton Vantage automated systems and liquid handling platforms using Venus software.
• Enzymatic Process Optimization: Design and execute enzymatic reactions with a focus on in vitro transcription and enzyme kinetics.
• Quality Control & Analysis: Perform comprehensive nucleic acid purification and characterization using advanced analytical techniques.
• Data-Driven Decision Making: Design experiments and conduct quantitative data analysis to drive scientific conclusions.

Benefits

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs, and at least 14 weeks’ gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.