Research Associate -III

About the role

This position supports the Systems Pharmacology and Biomarkers Rheumatoid Arthritis lab-based group to assist with pharmacodynamic assay development for phase 1 clinical studies and sample processing and analysis for larger phase 3 clinical studies.

Responsibilities

• Perform high-throughput RNA isolation and associated QC procedures from a variety of clinical sample types
• Perform protein assays on clinical samples
• Develop and execute cell-based assays to generate gene signatures of inflammatory disease pathways
• Use flow cytometry techniques to determine responses in individual cell types
• Assist in maintaining laboratory instruments and supplies in a clean and safe laboratory environment
• Aid in data analysis and interpretation using various computer programs, including MS Excel, GraphPad, etc.
• Manage large sample libraries and data sets

Requirements

• State-of-the-art knowledge in molecular and cellular biology
• Experience with ELISA (including MSD, Luminex, R&D Systems, etc), RNA isolation, Taqman qPCR, mammalian cell culture, and flow cytometry
• Familiarity with proper Biosafety procedures for working with human samples
• Experience performing high-throughput analysis of human samples, including the use of laboratory automation
• Must be highly organized and capable of handling several projects simultaneously
• Good interpersonal communication skills
• Self-motivated, productive, and excellent computer, communication, and scientific problem-solving skills

Qualifications

• BS degree in Biology, Biotechnology or related field plus minimum 5 years additional laboratory experience
• OR MS with 2 additional years of laboratory experience