Research Associate I, Platform Reagents & Assay Support

About the role

The Research Associate I, Platform Reagents & Assay Support (PRAS) role at BigHat Biosciences is aimed at individuals who are self-motivated and eager to support the in-house reagent manufacturing and quality control efforts. This role supports the Milliner platform and is part of the Lab Science department.

Responsibilities

• Execute automated and manual high-throughput reagent manufacturing and QC workflows to support data generation across BigHat’s production assay suite.
• Keep detailed records of all reagent lot manufacturing and QC events using BigHat’s documentation tools, and clearly communicate results and challenges.
• Contribute to reagent lot performance monitoring, and assist with troubleshooting efforts as needed.
• Collaborate on the creation of laboratory standard operating procedures (SOPs) for reagent manufacturing and QC.
• Collaborate closely with BigHat team members to identify, design, and implement critical process and operational improvements to workflows and laboratory systems.
• Operate automated liquid handlers and analytical instruments to ensure all lab and platform operations run efficiently.

Requirements

• BS in Biology or Chemistry, with 1+ year(s) of industry experience.
• Experience in reagent manufacturing and quality control, process execution, and troubleshooting.
• Hands-on experience with, or interest in, automated liquid handlers (e.g. Hamilton, OpenTrons, Tecan, Agilent systems).
• Experience with LIMS is a nice-to-have.
• Experience with molecular biology techniques and general lab practices.
• Efficient time management and ability to work on several projects simultaneously, in a dynamic start-up environment.
• Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
• Excellent record keeping abilities to document experimental work and analytical data.
• Nice-to-haves include previous experience working with barcoding systems and automated tube/plate labelers, inventory tracking, and experience with Google Workspace tools (Docs, Sheets, Slides, etc.).

Skills

• Knowledge and expertise in Biology or Chemistry.
• Experience in reagent manufacturing and quality control.
• Hands-on experience with automated liquid handlers.
• Experience with molecular biology techniques and general lab practices.
• Time management and project management skills.
• Interpersonal and communication skills.
• Record keeping abilities.
• Interest or experience with Google Workspace tools.

Total Rewards

The salary range for this position is $75,000 - $88,000, plus bonus, options, and benefits. Compensation will vary based on job-related knowledge, skills, and experience. An actual compensation amount will be confirmed in writing at the time of the offer.

About BigHat Biosciences

BigHat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology. We integrate a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases. BigHat is a Series B biotech outside San Francisco with a team-oriented, inclusive, and family-friendly culture. Our broad pipeline of wholly-owned and partnered therapeutic programs spans many disparate indications with high unmet need, such as cancer, inflammation, and infectious disease. BigHat has raised >$100M from top investors, including Section 32, a16z, and 8VC.