Research Associate I - In Vitro

About the role

The Research Associate I will support laboratory operations and preclinical studies focused on safety, efficacy, and toxicity evaluation of client drug candidates. This role is ideal for an early-career scientist with hands-on laboratory experience who is interested in developing expertise across histology, flow cytometry, cell-based assays, multiplex immunoassays, and biomarker analysis within a Contract Research Organization (CRO) environment.

Responsibilities

• Assist with tissue trimming, embedding, sectioning (microtomy and cryotomy), and slide preparation from preclinical study specimens.
• Perform routine histological staining and immunohistochemistry (IHC) procedures.
• Support digital slide scanning, image archiving, and basic tissue evaluation activities.
• Maintain sample tracking and documentation throughout study execution.
• Prepare biological samples including blood, tissues, and cultured cells.
• Perform surface and intracellular staining procedures.
• Operate flow cytometry instrumentation and assist with data analysis using FlowJo or similar software.
• Execute routine cell culture and cell-based assays to evaluate drug activity, potency, cytotoxicity, and mechanism of action.
• Support assay optimization and troubleshooting activities.
• Perform cytokine and biomarker analysis using the Meso Scale Discovery (MSD) platform.
• Prepare standards, controls, and study samples according to protocols.
• Operate absorbance, fluorescence, and luminescence plate readers.
• Perform ELISA and other plate-based assays while ensuring data quality and accuracy.
• Accurately record experimental procedures, observations, and results in laboratory notebooks and electronic systems.
• Absorb data compilation, analysis, and report preparation.
• Maintain complete and audit-ready study documentation in compliance with GLP requirements.
• Support preparation of study summaries and client deliverables.
• Execute laboratory activities in accordance with approved SOPs, study protocols, GLP requirements, and EHS standards.
• Assist with laboratory organization, inventory management, and reagent preparation.
• Support equipment maintenance, calibration, and troubleshooting activities.
• Participate in laboratory quality initiatives and continuous improvement efforts.
• Work closely with scientists, study directors, and laboratory personnel to support ongoing research projects.
• Contribute to cross-functional activities involving In Vivo Operations, Bioanalytical Sciences, and Quality Assurance teams.
• Contribute to a positive, collaborative, and client-focused laboratory environment.
• Follow all EHS policies, procedures, and laboratory safety requirements.
• Participate in safety training and compliance initiatives.
• Promote a culture of safety, accountability, and scientific integrity.

Qualifications

• Bachelor's degree in Biology, Immunology, Molecular Biology, Pharmacology, Biomedical Sciences, or a related scientific discipline.
• 1–3 years of hands-on laboratory experience in an academic, biotechnology, pharmaceutical, CRO, or research environment.
• Experience with one or more of the following laboratory techniques: Histology, Flow Cytometry, Cell Culture, Cell-Based Assays, ELISA, MSD Platform.
• Strong attention to detail and commitment to scientific accuracy.
• Excellent organizational and time-management skills.
• Strong written and verbal communication skills.
• Ability to work independently while contributing effectively within a team environment.
• Proficiency with Microsoft Office Suite, including Word, Excel, and Outlook.