Research Associate I – Imaging

About the role

The Allen Institute accelerates science for a healthier world through large-scale research designed to answer some of the most complex questions in biology. Our multi-disciplinary teams generate foundational knowledge, tools, and data to understand how our brain, cells, and immune system work. We share our work openly so others can build on it, move faster, and ask bigger questions. We drive discovery forward and create new possibilities for improving human health. The goal of the Brain Science accelerator is to produce three interlocking resources: cell type atlases that catalog every kind of brain cell across ages and species, connectomes that chart the brain's intricate wiring, and a knowledge platform that knits it all together with powerful analysis tools. Every dataset is freely shared, so discoveries made here fuel discoveries everywhere. We are looking for a Research Associate I as part of an interdisciplinary team working on spatial transcriptomics. The goal of our team is to produce high quality in situ hybridization data in order to characterize cell types in the brain.

Responsibilities

• Operate fluorescence imaging microscopes
• Handling of mouse and human tissue
• Perform multiple histological staining processes (Nissl, IHC, Biocytin, ISH)
• Prepare and assemble custom slides and imaging chambers
• Operate MERSCOPE, Xenium and any other imaging equipment within the team
• Compile, process and analyze data; evaluate and communicate research results
• Evaluate, calibrate, and troubleshoot experiment quality and instrument functionality
• Contribute to a rigorously scientific, cohesive and efficient team environment
• Maintain accurate laboratory documentation using established methods, which may include Microsoft Office, Custom Laboratory Information Management System (LIMS), and other packages
• Follow Standard Operating Procedures, good laboratory practices, and comply with all regulatory requirements
• Other duties as assigned

Requirements

• Bachelor’s degree in a life science or related field
• Basic knowledge of neuroscience and cell biology

Qualifications

• Exceptional manual dexterity and attention to detail
• Strong scientific communication skills (written and oral)
• 0-2 years experience working in a laboratory setting