Research Associate 2

About the role

The SCCC department at the University of Miami is seeking a Full Time Research Associate 2 to join their team at the UHealth Medical Campus in Miami, FL.

Responsibilities

• Conduct laboratory assignments, including preparing and preserving peripheral blood mononuclear cells (PBMC) from blood samples.
• Participate in the scheduling and performance of experiments related to immunology and leukocyte biology studies in a research laboratory.
• Conduct experimental procedures and maintain accurate records; participate in the processes of interpreting experimental data and assist in solving technical protocol execution problems.
• Operate routine scientific laboratory equipment.
• Provide technical support in various procedures in the laboratory, including collection and/or processing of specimens, performance of standard immunological techniques and molecular biology assays, assisting with scientific literature searches, and providing support in the preparation of reports.

Qualifications

• Bachelor’s Degree in Microbiology, Immunology or Biology preferred.
• Minimum 2 years of relevant experience.
• Prior experience in an academic research laboratory setting, experience with processing blood samples, performing flow cytometry, and advanced knowledge in Biology is strongly preferred.

Department specifics

This position involves performance of a variety of experiments in support of research in bone marrow transplantation and variety of cellular immunotherapies, especially adoptive T cell therapies-CAR T cells, in the Division of Transplant and Cell Therapy. In Green Lab, we study mechanisms of relapse and resistance to existing cellular therapy approaches, especially CAR T cells. The major goal of our lab is to generate preclinical data for clinical translation. Experience and knowledge of the immune system is essential.

Additional Duties

• Conduct laboratory assignments, including preparing and preserving peripheral blood mononuclear cells (PBMC) from blood samples and generating CAR T cells.
• Participate in the scheduling and performance of experiments related to immunology and leukocyte biology studies in a research laboratory.
• Conduct experimental procedures and maintain accurate records; participate in the processes of interpreting experimental data and assist in solving technical protocol execution problems.
• Operate routine scientific laboratory equipment.
• Provide technical support in various procedures in the laboratory, including collection and/or processing of specimens, performance of standard immunological techniques and molecular biology assays, assisting with scientific literature searches, and providing support in the preparation of reports.
• Capable of conducting experiments on aseptic cell culture including working on isolation, characterization and assay set up with primary human and murine immune cells, tumor cell lines or primary patient-derived cells.
• Work on production, maintenance and cryopreservation of CAR T cells and in vitro efficacy assays.
• Capable of working with mouse models of cancer after appropriate training per institutional guidelines - Animal handling and processing mouse samples for downstream analysis.
• Assist with scientific literature searches and updating of laboratory bibliography, and literature searches for references to address technical problems.
• Provide support in the preparation of reports of relevant findings in manuscripts for submission to journals, in grant proposals to funding agencies, and presentation of data in laboratory meetings and other venues.
• Provide support in preparation of required monthly/quarterly/annual reports including grant progress reports, environmental health and safety, etc.

Education & Experience

• B.S. degree in Microbiology, Immunology or Biology.
• Prior experience in an academic research laboratory setting required.
• Knowledge in molecular biology-immunology, CAR T cells is a plus.
• Should have considerable knowledge of laboratory equipment, methods and materials, and safety practices in a research setting.

Benefits

The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.