Raven StealthCo- Director/Senior Director, Biology

About the role

The company is in the discovery stage and plans to invest significantly in its emerging oligo delivery platform. Its focus areas are supported by highly predictive animal models with strong translatability to humans, offering a potentially rapid and efficient path to the clinic.

The Senior Director/Director Biology will report directly to the Head of Research/CSO. This individual will work closely with cross-functional leaders to translate the delivery platform into therapeutic programs with deep biological insights.

Responsibilities

• Build a research team of 3 while strategically leveraging consultants and CROs to accelerate early-stage discovery
• Lead a deep understanding of initial indication area biology by developing relationships with KOLs and extending further insights into the MOA of lead target(s) utilizing physiological and next-generation “omic” measurement tools
• Synthesize large datasets alongside mechanistic insights in cell biology and physiology to identify and prioritize novel targets actionable via company's platform
• Develop and own the suite of in vitro and in vivo assays needed for lead indication biology, including endpoint measurements for target manipulation across relevant cell types
• Lead and manage CRO partnerships supporting in vivo pharmacology, including design and evaluation of readouts across relevant disease models
• Collaborate with the VP of Delivery to analyze the biodistribution and pharmacodynamic metrics of the delivery platform, including assessments of proximal oligonucleotide effects on target genes (e.g. IHC, spatial transcriptomics, and mass spectrometry)
• Contribute to company-level strategic decisions on target and program selection, with particular attention to how biology findings inform platform development
• Communicate strategy and progress to internal and external stakeholders, including supporting fundraising efforts and strategic partnering as the company matures
• Track developments in lead indication biology and the competitive landscape

Qualifications

The ideal candidate brings demonstrated success delivering preclinical therapeutic programs, with deep mastery of at least one relevant area of biology, significant in vivo pharmacology experience, and a track record of translating novel ideas into rigorous, reproducible results.

Prior experience in our specific indication is a plus but not a requirement. This person will also represent the company credibly to the Board, investors, and the broader biotechnology community, and must be an effective mentor and manager.

We are building a culture where the science and the team come first; this person should embody that ethos and bring the interpersonal range to lead effectively within it.

From an educational perspective, we are seeking an individual with a Ph.D. and/or M.D. in a relevant discipline such as chemistry or protein engineering.