Protein Scientist

Key Responsibilities

• Perform and analyze affinity and kinetics measurements of antibodies produced in our high-throughput production facility
• Implement and troubleshoot workflows for biophysical and functional characterization of IgG and VHH, including analytical SEC, DLS, DSF, HIC, and additional downstream assays as needed.
• Serve as technical lead for protein characterization and help train and assist manufacturing assistants with execution of assays
• Author technical documents, protocols, training guides, and validation reports to ensure smooth process implementation and knowledge transfer.
• Analyze complex experimental datasets and contribute to data-driven troubleshooting and continuous process improvement.
• Collaborate in cross-functional project teams representing protein characterization in core team meetings and contributing to strategic decisions.
• Document work in electronic lab notebooks and communicate results to stakeholders clearly and regularly.

Qualifications And Required Skills

• Ph.D. in Protein Chemistry, Biochemistry, Molecular Biology, or a related field, or M.S. with 2–5 years of relevant industry experience.
• Strong hands-on experience in protein purification and characterization techniques.
• Experience characterizing affinity/kinetics (KD, ka, kd) of protein/target interactions using SPR or BLI
• Familiarity with biophysical methods for antibody developability such as SEC, DLS, DSF, HIC, ac-sins, enzymatic activity assays, among others.
• Background in protein chemistry and experience characterizing antibodies is strongly preferred.
• Excellent problem-solving skills, scientific judgment, and attention to detail.
• Strong interpersonal and communication skills with the ability to work in a collaborative, cross-disciplinary environment.
• Ability to troubleshoot, train, and mentor others in experimental workflows and data interpretation

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.