Process Development Engineer IV, Upstream

About the role

The Process Development Engineer IV supports upstream cell culture development for both early- and late-stage biotherapeutics programs. In this role, you will design and execute studies, generate and interpret data, and advance processes using a range of upstream technologies, including bench-top bioreactors, Ambr microscale bioreactors, shake flasks, WAVE bioreactors, and high-throughput purification systems.

Responsibilities

• Support the design and execution of upstream development studies across early- and late-stage programs
• Collaborate with upstream, downstream, and analytical teams as part of cross-functional development efforts
• Operate and troubleshoot cell culture systems, including bench-top bioreactors, Ambr, shake flasks, WAVE bioreactors, and high-throughput purification systems
• Utilize DeltaV or similar control systems to support process execution and data collection
• Maintain accurate and timely documentation in electronic laboratory notebooks
• Analyze process data, interpret results, and summarize findings to support development decisions
• Prepare technical reports, study summaries, and supporting documentation
• Learn and apply artificial intelligence and in silico tools to enhance process understanding and efficiency

Requirements

• Bachelor’s degree with 5+ years, or Master’s degree with 3+ years of relevant experience in biochemical engineering, chemical engineering, biotechnology, biology, or related field
• Experience in biotherapeutics upstream process development
• Hands-on experience with upstream unit operations, including bioreactors (bench-top and Ambr), shake flasks, and WAVE systems
• Working knowledge of DeltaV or similar process control systems
• Experience using electronic laboratory notebooks
• Strong data analysis and technical writing skills
• Solid understanding of upstream cell culture process development
• Ability to learn and apply new tools and technologies, including AI and in silico methods
• Strong attention to detail with the ability to work independently and collaboratively
• Proven ability to contribute to team objectives and support broader project goals