Process Development Engineer II, Analytical Sciences: Synthetic and Bioconjugation Scale-Up

About the role

The Process Development Engineer II, Analytical Sciences: Synthetic and Bioconjugation Scale-Up, serves as the analytical lead to develop fit-for-purpose analytical methods to characterize critical intermediates (small molecules, siRNA, and/or peptides) to support Regeneron's growing and diverse bioconjugate pipeline. This role involves leading and implementing analytical deliverables, coordinating internal and external analytical deliverables, and providing technical support and troubleshooting to ensure analytical activities do not impede program milestones.

Responsibilities

• Design and execute analytical testing, method development and characterization of critical intermediates to enable bioconjugate development.
• Compile, analyze, and interpret complex datasets; connect key findings across experiments and propose clear, actionable next steps.
• Communicate results and recommendations clearly to technical and non-technical audiences to enable timely, data-driven decisions.
• Serve as the analytical lead for critical intermediates and bioconjugates; coordinate internal and external analytical deliverables (development, transfer, and troubleshooting) to support program milestones.
• Provide technical support and troubleshooting to receiving labs to keep analytical activities off the critical path.
• Author high-quality documentation (e.g., procedures, method development reports, characterization reports, ELN entries) to support program timelines.
• Build and improve business workflows for documentation standardization, data digitization, and sample management.
• Maintain compliance with lab and environmental safety and promote a safe lab culture.
• Support equipment upkeep, troubleshoot, maintain an organized workspace, and proactively plan for lab resources.
• Train and mentor peers and junior team members as needed (directly and/or indirectly).

Requirements

• Bachelor's degree in analytical chemistry, biochemistry, biology, chemical engineering, or a related field.
• 6+ years of relevant experience with hands-on experience in analytical method development for synthetic molecules (e.g., small molecules, PEG, peptides, and oligos).
• Experience with electrophoresis, HPLC, MS, UV spectroscopy and associated software (e.g., Empower).
• Experience transferring methods to internal/external development labs and troubleshooting.
• Experience serving as an analytical lead, working with internal teams and external CDMOs.
• Strong written and verbal communication skills, including the ability to present data clearly to diverse audiences.
• Ability to work with minimal guidance and collaboratively across cross-functional teams, with strong attention to detail and documentation practices.
• Demonstrated initiative, learning agility, and a growth mindset in a fast-paced environment.
• Experience with antibodies and/or bioconjugates is strongly preferred.

Qualifications

• Hands-on experience with analytical techniques for synthetic molecules (e.g., small molecules, PEG, peptides, and oligos).
• Experience with electrophoresis, HPLC, MS, UV spectroscopy and associated software (e.g., Empower).
• Experience with antibody and/or bioconjugate analysis.

Skills

• Hands-on experience with analytical method development for synthetic molecules (e.g., small molecules, PEG, peptides, and oligos).
• Experience with electrophoresis, HPLC, MS, UV spectroscopy and associated software (e.g., Empower).
• Experience with antibody and/or bioconjugate analysis.

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

Pay

$93,900.00 - $153,300.00 annually

Schedule

Full-time