Process Development Engineer I, Purification Development

About the role

The Process Development Engineer will be responsible for purification process development and supporting the purification of various pre-clinical biological molecules. This individual will also assist in technology transfers to internal manufacturing sites.

Responsibilities

• Perform process development for pre-clinical and clinical processes
• Document experiments, results, and findings in electronic laboratory notebook
• Read and understand scientific literature and technical documentation
• Execute experimental plans to verify literature findings with direction and prepare comparison of internal data to literature for review with manager
• Maintain instruments and tackle instrumental/experimental problems
• Develop technology and automation to increase process throughput and efficiency of preclinical manufacturing; support of improvement initiatives
• Present work at group and department meetings
• Build relationships within subgroup to support shared goals and may train peers and indirectly lead, guide, and assist co-op students/interns
• Proactively assist others in execution of experiments and know when to ask for help from peers

Requirements

• Bachelor’s and/or Master’s degree in Chemical Engineering, Biochemical Engineering, or Biochemistry
• 0 - 3 years’ experience in the biotech or pharmaceutical industry
• A strong fundamental understanding of various protein purification and technology transfer principles
• Experience with Downstream Development and with equipment like: Akta Avant, Akta Pilot, Akta Process Skid, Disc Stack Centrifuge, Depth filtration, Tangential flow filters, Normal flow filters, Chromatographic columns, HPLC, UPLC, Ultrafiltration/Diafiltration skid, Laminar Flow Hood, Chemical Fume hood, Empower, Unicorn, JMP, LIMS, PI Historian
• Experience with robotic liquid handlers, Raman spectroscopy, and/or software programming

Qualifications

• Initiative and drive to complete ambitious tasks and learn new technologies
• Contribute to lab equipment maintenance and safety to help create a safe, effective and efficient working environment
• Anticipate and recognize potential problems with laboratory supplies / equipment and act to prevent and tackle problems
• Keep up with SOP training and/or compliance responsibilities

Skills

• Strong fundamental understanding of various protein purification and technology transfer principles
• Experience with Downstream Development and with equipment like: Akta Avant, Akta Pilot, Akta Process Skid, Disc Stack Centrifuge, Depth filtration, Tangential flow filters, Normal flow filters, Chromatographic columns, HPLC, UPLC, Ultrafiltration/Diafiltration skid, Laminar Flow Hood, Chemical Fume hood, Empower, Unicorn, JMP, LIMS, PI Historian
• Experience with robotic liquid handlers, Raman spectroscopy, and/or software programming

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• Annual bonuses or other incentive plans
• Equity awards
• Pension or retirement benefits
• 401(k) company match
• Health and wellness programs
• Fitness centers
• Insurance benefits (e.g. medical, dental, vision, life and disability)
• Paid time off
• Family support benefits

Pay

$80,300.00 - $131,100.00 annually

Schedule

Full-time