Principal Toxicologist

About the role

Join Altria’s Harm Reduction vision and journey to responsibly lead the transition of adult smokers to a smoke-free future. As a Principal Toxicologist, you will contribute to the development and regulatory submission of reduced-risk tobacco and nicotine products.

Responsibilities

• Serve as a subject matter expert in and provide scientific recommendations for regulatory and/or mechanistic toxicology testing as part of overall toxicological risk assessments for potentially reduced-risk tobacco products
• Lead data consolidation, integration and analysis for Biological Sciences Insights team aimed to incorporate insights into exposure-led risk assessments
• Design and lead GLP and non-GLP studies on diverse test materials (individual chemicals, mixtures, aerosols, extracts, etc.) across various exposure regimens as study monitor and sponsor representative
• Occasional travel (10-20%) to external labs for lab selection, inspection, study monitoring, etc.
• Prepare results for internal communications and regulatory submissions
• Identify data gaps and develop strategies to address
• Lead and participate in cross-functional teams, providing toxicological expertise while representing BSI and the Pre-Clinical team
• Proactively engage with external scientific communities and represent the company via external presentations and peer-review publications
• Maintain awareness of new approach methodologies (NAMs) to advance our preclinical testing program

Requirements

• PhD in toxicology or closely related field with 5+ years of experience (minimum of 8 years of experience with MSc)
• Strong experience in risk assessment/analysis in a regulatory environment (experience in the tobacco environment is a plus)
• Demonstrated ability to analyze/synthesize data from multiple lines of evidence to develop meaningful insights and conclusions
• Expertise as study director or study monitor in the conduct of preclinical toxicity studies is required with hands-on experience in the conduct of in vivo studies being highly desirable
• Experience in NAMs, such as PBPK modeling and/or BMD modeling, in support of chemical and product risk assessment is highly desired with experience in bioinformatics and/or computational toxicology preferred
• Good project management skills, attention to detail, as well as outstanding verbal and written communication skills for presenting and communicating results/data to both scientists and non-scientists are required
• Strong leadership skills with ability to effectively work within cross-functional settings and with minimum supervision

Qualifications

• PhD in toxicology or closely related field with 5+ years of experience (minimum of 8 years of experience with MSc)

Skills

• Preclinical testing (e.g., in vitro, in vivo, in silico, etc.)
• Risk assessment/analysis in a regulatory environment
• Data analysis and synthesis
• Study design and execution
• Project management
• Communication and presentation skills
• Leadership and teamwork
• New approach methodologies (NAMs)

Benefits

Altria offers a competitive salary range of $119,600.00 - $173,450.00, along with a variety of benefits including:

• Flexible and remote work options
• Comprehensive medical, dental, and vision coverage
• Paid parental and bonding leave
• Professional development stipends
• Volunteer days
• Shared commitment to making a difference

Pay

The starting salary is based on but not limited to experience, knowledge, and qualifications in determining compensation decisions.

Schedule

A 37.5-hour workweek is offered.