Principal Scientist (Director), Translational Medicine - Infectious Diseases

We need to output HTML fragment with sections: headings

for sections like About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. Only include sections if posting has real specific content. We must not repeat job title as heading. No Job ID etc. Remove boilerplate, navigation, legal, EEO, etc. Also remove application instructions, duplicated lines, etc. We need to preserve all substantive information. Let's parse the posting: - Job Description: "We have an exciting opportunity for a physician-scientist to join our group as a Principal Scientist (Clinical Director) in Translational Medicine/Early Clinical Development in the Infectious Diseases Therapeutic Area." - Then description of Translational Medicine responsibilities. - "We are seeking a highly qualified individual for a position in our group. Candidates must have a strong background in basic and/or clinical translational research and a desire to work collaboratively with functional area partners across therapeutic areas and stages of development." - Then "Translational Medicine Is Specifically Responsible For" bullet list (though not bullet but sentences). We need to extract duties. - Then "Success depends on the integrity, knowledge, imagination, creativity, skill, versatility and teamwork of the people in the group. To this end, we strive to create an environment of mutual respect, encouragement, and teamwork." - Education Requirements: MD or MD/PhD - Primary Responsibilities For The Principal Scientist Include The Following: then a long list of responsibilities. - Required Skills: Clinical Research, Early Clinical Development, Infectious Disease, Translational Medicine - Preferred Skills: (none listed? Actually "Preferred Skills Current Employees apply HERE Current Contingent Workers apply HERE US And Puerto Rico Residents Only" - that's not skills; it's instructions. So no preferred skills content.) - Then "Requirements" section (maybe duplicate). Actually after Preferred Skills there is "Requirements As an Equal Employment Opportunity Employer..." which is EEO boilerplate, we should remove. - Then salary range: $260,300.00 - $409,700.00 - Then benefits description. - Then application instructions etc (remove). - Then location specifics: San Francisco Residents Only..., Los Angeles Residents Only..., Search Firm Representatives..., Employee Status Regular Relocation: No relocation VISA Sponsorship No Travel Requirements 10% Flexible Work Arrangements Hybrid Shift Not Indicated Valid Driving License No Hazardous Material(s) n/a Job Posting End Date 09/24/2026 etc. Many of these are metadata; we should fold minor metadata into a short

or drop it. The instruction: "do NOT put Job ID / requisition numbers as headings — fold minor metadata into a short

or drop it." So we can include a short paragraph for things like relocation, visa sponsorship, travel, flexible work, shift, driving license, hazardous materials, posting end date maybe? But we should avoid boilerplate like EEO, application instructions, etc. We need to decide which sections to include: About the role (maybe a brief summary), Responsibilities (the primary responsibilities list), Requirements (education MD/MD/PhD plus maybe required skills?), Qualifications (maybe required skills?), Skills (maybe required and preferred?), Benefits, Pay, Schedule. We need to avoid filler sections like "Schedule" if not specified. The posting mentions "Travel Requirements 10%" and "Flexible Work Arrangements Hybrid". That's schedule-ish. Could include a Schedule section with that info. Pay: we have salary range. Benefits: we have description. Responsibilities: we have the primary responsibilities list. Requirements: education MD/MD/PhD. Qualifications: maybe required skills? Could combine required skills into Qualifications or Skills. Skills: required skills list. We need to avoid duplication. Let's extract substantive content: About the role: The opening paragraph: "We have an exciting opportunity for a physician-scientist to join our group as a Principal Scientist (Clinical Director) in Translational Medicine/Early Clinical Development in the Infectious Diseases Therapeutic Area. Translational Medicine at our Research Division is responsible for early clinical development of novel therapeutics, working in close collaboration with our discovery scientists and late-stage clinical researchers. The Infectious Diseases Therapeutic Area specifically focuses on translational and clinical development of anti-infectives, both for treatment and for prophylaxis indications. We are seeking a highly qualified individual for a position in our group. Candidates must have a strong background in basic and/or clinical translational research and a desire to work collaboratively with functional area partners across therapeutic areas and stages of development." That's good. Responsibilities: The "Primary Responsibilities For The Principal Scientist Include The Following" list. Let's extract each bullet as

. List items: - Working with basic science teams on specific diseases and therapeutic areas, providing clinical expertise for identification and validation of novel targets, including the design of preclinical and clinical experiments to validate targets and/or pathways, and leveraging this work for development of novel therapeutics - Working with cross-functional teams including discovery scientists, pharmacologists, toxicologists, and other specialists to advance novel therapeutics from preclinical development into clinical development - As a key member/leader of an early development team, working in close collaboration with internal and external staff and scientists (including discovery research, biostatistics, drug metabolism, modeling and simulation, regulatory affairs, and global clinical trials operations) for the design and execution of early clinical development strategy - Taking a lead role in developing and executing clinical pharmacology studies for programs in all phases (I – IV) of development, including formulation or device changes, drug-drug interaction studies, and studies in special populations - Providing early phase/clinical pharmacology support for programs through the regulatory filing process including preparation of supportive documents and presentations - Developing and executing studies to validate established and novel clinical biomarkers, including blood/tissue sampling, imaging, electrophysiological, wearable devices, and behavioral responses to study biological activity in humans - Providing clinical and scientific expertise to assess internal and external opportunities for partnership - Engaging with the broader internal and external scientific community in disease or therapeutic areas of interest, including via consultations with scientific/academic thought leaders, preparation of posters and publications, and attendance/presentation at conferences - Working broadly with key functions across the company at research sites around the world. Also earlier there were responsibilities from "Translational Medicine Is Specifically Responsible For" but those are similar; we might incorporate them but they may duplicate. However we should preserve all substantive info; we can include them as part of responsibilities as well. Let's extract those: - Contributing to the identification of novel targets by partnering with Discovery Sciences to bring a clinical perspective into the earliest stages of target identification and validation, and to execute clinical studies to evaluate the relevance of potential targets to human disease in order to justify full development. - Leadership of the early clinical development strategy for novel therapeutic programs from the preclinical stage through Phase 1 studies of safety, tolerability, pharmacokinetics and pharmacodynamics, to Phase 2 studies demonstrating Proof-of-Concept and enabling Phase 3 clinical trials. - Development of biomarker strategies through cross-functional teams that advance therapeutics from First-in-Human studies through clinical Proof-of-Concept. This includes experimental medicine studies to establish and/or validate biomarker platforms. - Development and execution of clinical pharmacology strategies to support later stages of development, from Phase 3 through to worldwide regulatory applications. These are also responsibilities; we can include them. We should avoid duplication but it's okay to have overlapping content; but better to combine unique points. Let's combine all responsibilities into a single list, ensuring we cover all. Now Requirements: Education Requirements MD or MD/PhD. Also maybe "Candidates must have a strong background in basic and/or clinical translational research and a desire to work collaboratively..." could be part of Requirements or Qualifications. We can put that under Requirements as a paragraph. Qualifications: maybe not separate; we could treat Required Skills as Qualifications. Skills: Required Skills list: Clinical Research, Early Clinical Development, Infectious Disease, Translational Medicine. Preferred Skills: none given. Benefits: "We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits." Pay: Salary range $260,300.00 - $409,700.00 plus mention of annual bonus and long-term incentive. Schedule: Travel Requirements 10%, Flexible Work Arrangements Hybrid, Shift Not Indicated, etc. Also maybe "Relocation: No relocation", "VISA Sponsorship No", "Valid Driving License No", "Hazardous Material(s) n/a". These are minor metadata; we could fold into a short paragraph under Schedule or maybe a separate "Additional Information" but we only have allowed headings: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. So we can put schedule-related info under Schedule. We should not include headings for empty sections. Thus final HTML:

About the role

...

Responsibilities

• ...
...

Requirements

Education: MD or MD/PhD. Candidates must have a strong background in basic and/or clinical translational research and a desire to work collaboratively with functional area partners across therapeutic areas and stages of development.

Skills

• Clinical Research
• Early Clinical Development
• Infectious Disease
• Translational Medicine

Benefits

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

Pay

The salary range for this role is $260,300.00 - $409,700.00. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

Schedule

Travel requirements: approximately 10%. Flexible work arrangements: hybrid. Shift: not indicated. Relocation: not offered. Visa sponsorship: not provided. Valid driver's license: not required. Hazardous materials: none.

We need to ensure we didn't include boilerplate like EEO, application instructions, etc. We removed those. Check for any leftover boilerplate: We removed "Current Employees apply HERE Current Contingent Workers apply HERE US And Puerto Rico Residents Only", "Our company is committed to inclusion...", "As an Equal Employment Opportunity Employer...", "For more information about personal rights...", "We are proud to be a company...", "Learn more about your rights...", "The application deadline for this position is stated on this posting.", "San Francisco Residents Only...", "Los Angeles Residents Only...", "Search Firm Representatives Please Read Carefully...", "Employee Status Regular Relocation: No relocation VISA Sponsorship No Travel Requirements 10% Flexible Work Arrangements Hybrid Shift Not Indicated Valid Driving License No Hazardous Material(s) n/a Job Posting End Date 09/24/2026 A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Requisition ID:R415168". We folded some of those into Schedule paragraph (travel, flexible work, relocation, visa, driving license, hazardous materials). We omitted posting end date and requisition ID as minor metadata; we could include them in Schedule paragraph as well but maybe drop. The instruction: "do NOT put Job ID / requis