Principal Scientist (Director), Translational Medicine - Infectious Diseases
About the Role
Translational Medicine at our Research Division is responsible for early clinical development of novel therapeutics, working in close collaboration with our discovery scientists and late-stage clinical researchers. The Infectious Diseases Therapeutic Area specifically focuses on translational and clinical development of anti-infectives, both for treatment and for prophylaxis indications. We are seeking a highly qualified individual for a position in our group. Candidates must have a strong background in basic and/or clinical translational research and a desire to work collaboratively with functional area partners across therapeutic areas and stages of development.
Responsibilities
- Working with basic science teams on specific diseases and therapeutic areas, providing clinical expertise for identification and validation of novel targets, including the design of preclinical and clinical experiments to validate targets and/or pathways, and leveraging this work for development of novel therapeutics
- Working with cross-functional teams including discovery scientists, pharmacologists, toxicologists, and other specialists to advance novel therapeutics from preclinical development into clinical development
- As a key member/leader of an early development team, working in close collaboration with internal and external staff and scientists (including discovery research, biostatistics, drug metabolism, modeling and simulation, regulatory affairs, and global clinical trials operations) for the design and execution of early clinical development strategy
- Taking a lead role in developing and executing clinical pharmacology studies for programs in all phases (I – IV) of development, including formulation or device changes, drug-drug interaction studies, and studies in special populations
- Providing early phase/clinical pharmacology support for programs through the regulatory filing process including preparation of supportive documents and presentations
- Developing and executing studies to validate established and novel clinical biomarkers, including blood/tissue sampling, imaging, electrophysiological, wearable devices, and behavioral responses to study biological activity in humans
- Providing clinical and scientific expertise to assess internal and external opportunities for partnership
- Engaging with the broader internal and external scientific community in disease or therapeutic areas of interest, including via consultations with scientific/academic thought leaders, preparation of posters and publications, and attendance/presentation at conferences
- Working broadly with key functions across the company at research sites around the world
Qualifications
- MD or MD/PhD
- Strong background in basic and/or clinical translational research
Skills
- Clinical Research
- Early Clinical Development
- Infectious Disease
- Translational Medicine
Pay & Benefits
Salary range: $260,300.00 – $409,700.00. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. Benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits including 401(k), paid holidays, vacation, and compassionate and sick days.