Principal Investigator

About the role

• Be part of a practice at the forefront of cutting-edge cancer care and advanced treatments
• Access opportunities for professional growth and continuing education
• Work alongside a collaborative and compassionate team of experts dedicated to making a difference
• Enjoy the convenience of multiple locations throughout the Capital Region
• Contribute to groundbreaking clinical trials that shape the future of oncology care
• Discover your career potential with a practice dedicated to excellence and innovation

Responsibilities

• Reporting Relationship: Works closely with site Clinical Operations leadership, Director of Nursing Services, START Executive Leadership, Chief Medical Officer, and Technology leadership; accountable for physician investigator activity at the site until a full-time Physician Investigator Site Leader assumes that responsibility, after which may transition to a defined ongoing role or complete the engagement.
• Engagement Model and Time Commitment: Structured in phases aligned to site readiness and go-live:
  • Pre-Launch (Months 2–3 before go-live): a few hours per week, focused on protocol and study selection input, credentialing, regulatory and IRB set-up, early staff engagement.
  • Final Month Before Go-Live: time commitment increases to approximately 16 hours per week, includes an on-site visit of up to one week at an established NYOH/START clinic to become familiar with START systems, workflows, and documentation standards.
  • Go-Live and Early Operations: continues at approximately 16 hours per week as the site's Principal Investigator, providing patient-facing and protocol oversight through the early operational period.
  • Transition: upon hire of a full-time Physician Investigator Site Leader, the Launch PI typically transitions out of the interim PI role; may remain engaged with the Phase 1 unit in an ongoing capacity of approximately 1–2 days per week thereafter.
• Pre-Launch Responsibilities: Support site readiness activities in partnership with Clinical Operations and Technology leadership, including protocol selection input, feasibility review, and study start-up sequencing; complete credentialing, privileging, and required regulatory documentation ahead of go-live; participate in site build-out planning, including capacity, staffing, and workflow design specific to Phase 1 requirements; complete on-site training at a reference NYOH/START clinic to gain familiarity with START systems, standard operating procedures, and documentation practices.
• Launch-Phase Physician Investigator Responsibilities: Serve as the site's Principal Investigator for enrolled protocols during the interim period, providing new patient consults, consent visits, safety follow-ups, and infusion oversight as required; ensure timely completion of protocol-required investigator activities, including data entry and safety reporting; serve as the point of clinical escalation for physician-dependent decisions at the site until a full-time Physician Investigator Site Leader is in place; coordinate with Nursing, Clinical Research Coordinators, Regulatory, and Marketing to support clinic operations and communication during the ramp-up period; provide input to site leadership on study selection and portfolio fit as the unit builds its early caseload.
• Transition and Ongoing Involvement: Support a structured handoff of patients, protocols, and site knowledge to the incoming full-time Physician Investigator Site Leader; where mutually agreed, continue in an ongoing capacity within the Phase 1 unit (approximately 1–2 days per week) following the transition to full-time leadership; provide mentorship to incoming and junior investigators as needed to support continuity of clinical research capability at the site.