Principal Computational Biology

About the role

This role is ideal for someone who loves operating at the frontier—combining deep biological intuition, computational creativity, and emerging AI capabilities to generate insights that can influence clinical development decisions and ultimately improve patient outcomes.

Location: New York City, NY (Hybrid model)

What will you do?

• Design and deploy innovative, state-of-the-art analytic approaches, including computational pipelines and agentic workflows, that improve outcomes for industry partnerships.
• Standardize and operationalize reusable approaches that can be broadly adopted across projects to improve scalability, reproducibility, and scientific consistency.
• Leverage agentic workflows to amplify the team’s analytical speed, creativity, and automation, contributing to a culture of technical excellence and continuous improvement.
• Establish blueprints for platform innovation and drive implementation with R&D cross-functional stakeholders.

Requirements

• Exceptional publications and accomplishments in a rigorous computational biology or computer science doctoral training program
• 8+ years relevant experience including at least 3+ years developing translational solutions in a biomedical industry setting
• Creative and innovative mindset - Problem solver with demonstrated track record of pushing scientific and technical boundaries
• AI-first, no-code mindset, preferably with experience designing and implementing agentic workflows with appropriate human-in-the-loop checkpoints
• Hands-on experience with machine learning methodologies and the ability to adapt, utilize and extend internal modeling frameworks
• Demonstrated experience translating technical work to clear, high-impact outcomes
• Expertise in distilling multi-faceted analyses into concrete conclusions with effective data visualizations and presentations

Desired personal traits

• You have superior skills and experience, and constantly strive to be world-class in what you do
• You are not afraid to break things because you know how to rebuild it better
• You move quickly to generate high-impact outcomes - but never sacrifice quality
• You have a growth mindset; you constantly challenge your own assumptions, push for continuous improvement, and disrupt status quo
• You influence effectively, including people of diverse backgrounds and cultures
• You are candid, authentic, and transparent
• You prioritize “We” over “I”
• You want to make an impact on humankind